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Open AccessDeep-learning-based gas identification by time-variant illumination of a single micro-LED-embedded gas sensor
Electronic nose (e-nose) technology for selectively identifying a target gas through chemoresistive sensors has gained much attention for various applications, such as smart factory and personal health monitor...
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Article
Open AccessRoles of PI3K pan-inhibitors and PI3K-δ inhibitors in allergic lung inflammation: a systematic review and meta-analysis
Meta-analysis can be applied to study the effectiveness of the summary estimates for experimental papers, producing objective and unbiased results. We investigated the effects of phosphoinositide-3-kinase (PI3...
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Article
Open AccessPhosphoinositide 3-kinase-delta could be a biomarker for eosinophilic nasal polyps
Nasal polyps (NP) cause diverse clinical symptoms of chronic rhinosinusitis (CRS). Chronic inflammation of sinonasal mucosa is known to be crucial in NP formation. We aimed to define the implications of phosph...
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Basics of Severe Asthma in Clinical Practice
Bronchial asthma is now widely recognized as a heterogeneous clinical syndrome consisting of various disease phenotypes with distinct observable molecular, cellular, morphological, functional, and clinical fea...
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Article
Open AccessEndoplasmic Reticulum Stress and Allergic Diseases
In this review, we will integrate recent knowledge on endoplasmic reticulum (ER) stress and allergy, thereby highlighting the therapeutic potential of ER stress in the context of precision medicine for allergi...
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Open AccessInhibition of endoplasmic reticulum stress alleviates lipopolysaccharide-induced lung inflammation through modulation of NF-κB/HIF-1α signaling pathway
Lipopolysaccharide (LPS) is involved in a variety of inflammatory disorders. Under stress conditions, endoplasmic reticulum (ER) loses the homeostasis in its functions, which is defined as ER stress. Little is...
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PI3Kγ activation is required for LPS-induced reactive oxygen species generation in respiratory epithelial cells
In this study, we investigated the molecular basis of reactive oxygen species (ROS) generation induced by lipopolysaccharide (LPS) in A549 cells—an alveolar epithelial cell line.
