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Article
Association between self-reported visual symptoms (suggesting cataract) and self-reported fall-related injury among adults aged ≥ 65 years from five low- and middle-income countries
Cataracts may increase risk for falls but studies on this topic from low- and middle-income countries (LMICs) are scarce. Therefore, we examined the cross-sectional association between self-reported visual sym...
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Article
Incidence, prevalence, and global burden of schizophrenia - data, with critical appraisal, from the Global Burden of Disease (GBD) 2019
Schizophrenia substantially contributes to the burden of mental disorders. Schizophrenia’s burden and epidemiological estimates in some countries have been published, but updated estimates of prevalence, incid...
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Article
Incidence, prevalence, and global burden of ADHD from 1990 to 2019 across 204 countries: data, with critical re-analysis, from the Global Burden of Disease study
Data on incidence, prevalence and burden of ADHD are crucial for clinicians, patients, and stakeholders. We present the incidence, prevalence, and burden of ADHD globally and across countries from 1990 to 2019...
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Article
Open AccessSociodemographic inequalities in mortality from drowning in the Baltic countries and Finland in 2000–2015: a register-based study
Drowning is an important public health problem. Some evidence suggests that the risk of drowning is not distributed evenly across the general population. However, there has been comparatively little research o...
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Article
The impact of pharmacological and non-pharmacological interventions on physical health outcomes in people with mood disorders across the lifespan: An umbrella review of the evidence from randomised controlled trials
People with mood disorders have increased risk of comorbid medical diseases versus the general population. It is paramount to identify interventions to improve physical health in this population.
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Article
Open AccessMap** age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018
Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is still among the leading causes of disease burden and mortality in sub-Saharan Africa (SSA), and the world is not on track to m...
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Article
Incidence, prevalence, and global burden of autism spectrum disorder from 1990 to 2019 across 204 countries
Autism spectrum disorder (ASD) substantially contributes to the burden of mental disorders. Improved awareness and changes in diagnostic criteria of ASD may have influenced the diagnostic rates of ASD. However...
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Article
Open AccessPrognostic accuracy and clinical utility of psychometric instruments for individuals at clinical high-risk of psychosis: a systematic review and meta-analysis
Accurate prognostication of individuals at clinical high-risk for psychosis (CHR-P) is an essential initial step for effective primary indicated prevention. We aimed to summarise the prognostic accuracy and cl...
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Article
Open AccessGlobal population attributable fraction of potentially modifiable risk factors for mental disorders: a meta-umbrella systematic review
Numerous risk factors for mental disorders have been identified. However, we do not know how many disorders we could prevent and to what extent by modifying these risk factors. This study quantifies the Popula...
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Article
Association of objective and subjective far vision impairment with perceived stress among older adults in six low- and middle-income countries
To assess the association between far vision impairment (objective and subjective) and perceived stress among older adults from six low- and middle-income countries (LMICs, i.e., China, Ghana, India, Mexico, R...
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Article
Open AccessSocial media use and mental health during the COVID-19 pandemic in young adults: a meta-analysis of 14 cross-sectional studies
Public isolated due to the early quarantine regarding coronavirus disease 2019 (COVID-19) increasingly used more social media platforms. Contradictory claims regarding the effect of social media use on mental ...
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Article
Correction: Differential expression of MicroRNAs in Alzheimer’s disease: a systematic review and meta-analysis
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Article
Differential expression of MicroRNAs in Alzheimer’s disease: a systematic review and meta-analysis
Alzheimer’s disease (AD) results in progressive cognitive decline owing to the accumulation of amyloid plaques and hyperphosphorylated tau. MicroRNAs (miRNAs) have attracted attention as a putative diagnostic ...
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Article
Physical activity and visual difficulties in 36 low- and middle-income countries
Data on the association between visual difficulty and physical activity (PA) from low- and middle-income countries (LMICs) are scarce. Thus, the aim of the study was to investigate the association between visu...
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Article
Open AccessAge at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies
Promotion of good mental health, prevention, and early intervention before/at the onset of mental disorders improve outcomes. However, the range and peak ages at onset for mental disorders are not fully establ...
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Article
Associations between cataract and multimorbidity: a cross-sectional study of 23,089 adults from Spain
Little is known about the association between cataract and multimorbidity. Therefore, the aim of the present study was to examine the relationship between cataract and chronic conditions and multimorbidity in ...
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Article
COVID-19: implications for immunosuppression in kidney disease and transplantation
The coronavirus disease 2019 (COVID-19) pandemic poses important challenges to the care of patients with immune-mediated kidney diseases and to kidney transplant recipients. Here, we discuss the management of ...
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Article
Open AccessEfficacy and acceptability of pharmacological and non-pharmacological interventions for non-specific chronic low back pain: a protocol for a systematic review and network meta-analysis
Despite the enormous financial and humanistic burden of chronic low back pain (CLBP), there is little consensus on what constitutes the best treatment options from a multitude of competing interventions. The o...
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Article
Hypertension in obesity: the role of hypothalamic inflammation
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Article
Regulatory T cells—an important target for cancer immunotherapy