![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessFactor Structure of the Difficulties in Emotion Regulation Scale among Early Adolescents: Results from the Adolescent Brain Cognitive Development Study
Emotion regulation (ER) deficits in early adolescence are associated with subsequent negative health consequences, including anxiety and depression. Yet, limited work has evaluated the factor structure of meas...
-
Article
Effect of Emotion Regulation Difficulties on Acute Smoking Urges Following a 35% Carbon Dioxide Challenge
Carbon dioxide (CO2) challenges produce uncomfortable anxious arousal sensations and can be leveraged to study how vulnerability factors influence smoking outcomes in contexts of acute distress. Emotion dysregula...
-
Article
Open AccessIntegrated intracellular organization and its variations in human iPS cells
Understanding how a subset of expressed genes dictates cellular phenotype is a considerable challenge owing to the large numbers of molecules involved, their combinatorics and the plethora of cellular behaviou...
-
Article
Open AccessErratum: Divergent activity of the gonadotropin-releasing hormone receptor gene promoter among genetic lines of pigs is partially conferred by nuclear factor (NF)-kB, specificity protein (SP)1-like and GATA-4 binding sites
-
Article
Open AccessDivergent activity of the gonadotropin-releasing hormone receptor gene promoter among genetic lines of pigs is partially conferred by nuclear factor (NF)-kB, specificity protein (SP)1-like and GATA-4 binding sites
Binding of gonadotropin-releasing hormone (GnRH) to its receptor (GnRHR) on gonadotropes within the anterior pituitary gland is essential to reproduction. In pigs, the GnRHR gene is also located near a genetic...
-
Article
Open AccessActivity of the porcine gonadotropin-releasing hormone receptor gene promoter is partially conferred by a distal gonadotrope specific element (GSE) within an upstream enhancing region, two proximal GSEs and a retinoid X receptor binding site
Regulation of gonadotropin-releasing hormone (GnRH) receptor (GnRHR) numbers on gonadotropes within the anterior pituitary gland represents a critical point for control of reproductive function. Binding of GnR...
-
Article
Co-treatment with vorinostat synergistically enhances activity of Aurora kinase inhibitor against human breast cancer cells
Aurora kinases (AKs) regulate multiple components of mitotic cell division in eukaryotic cells. Aurora A is frequently amplified or overexpressed in breast cancer cells leading to aberrant chromosome segregati...