4 Result(s)
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Jacqueline A. Maybin
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Article
Uterine bleeding: how understanding endometrial physiology underpins menstrual health
Menstruation is a physiological process that is typically uncomplicated. However, up to one third of women globally will be affected by abnormal uterine bleeding (AUB) at some point in their reproductive years...
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Article
Open AccessHypoxia and hypoxia inducible factor-1α are required for normal endometrial repair during menstruation
Heavy menstrual bleeding (HMB) is common and debilitating, and often requires surgery due to hormonal side effects from medical therapies. Here we show that transient, physiological hypoxia occurs in the menst...
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Article
Open AccessEndometrial apoptosis and neutrophil infiltration during menstruation exhibits spatial and temporal dynamics that are recapitulated in a mouse model
Menstruation is characterised by synchronous shedding and restoration of tissue integrity. An in vivo model of menstruation is required to investigate mechanisms responsible for regulation of menstrual physiology...
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Article
Steroid regulation of menstrual bleeding and endometrial repair
The ovarian steroid hormones progesterone and estradiol are well established regulators of human endometrial function. However, more recent evidence suggests that androgens and locally generated steroids, such...
