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Thiazolidinediones in prediabetes and early type 2 diabetes: What can be learned about that disease’s pathogenesis
Several clinical trials have shown a high success rate of thiazolidinediones (TZDs) in prediabetes and early type 2 diabetes. The presumed mechanism of this effect has shifted from the best known effect of the...
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Pathogenesis of Type 2 Diabetes Mellitus
The pathophysiology of type 2 diabetes is complex, with many different elements acting to cause the disease. This review proposes a sequence of events that is based on a careful analysis of the human and anima...
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Article
How is the insulin content regulated in nondiabetic hyperinsulinaemic, insulin resistant states? Study of spontaneously hypertensive rats
