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Article
Open AccessProfiles of mathematical deficits in children with dyslexia
Despite a high rate of concurrent mathematical difficulties among children with dyslexia, we still have limited information regarding the prevalence and severity of mathematical deficits in this population. To...
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Article
Exogenic basalt on asteroid (101955) Bennu
When rubble-pile asteroid 2008 TC3 impacted Earth on 7 October 2008, the recovered rock fragments indicated that such asteroids can contain exogenic material1,2. However, spacecraft missions to date have only obs...
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Article
Collisional history of Ryugu’s parent body from bright surface boulders
The asteroid (162173) Ryugu and other rubble-pile asteroids are likely re-accumulated fragments of much larger parent bodies that were disrupted by impacts. However, the collisional and orbital pathways from t...
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Article
Properties of rubble-pile asteroid (101955) Bennu from OSIRIS-REx imaging and thermal analysis
Establishing the abundance and physical properties of regolith and boulders on asteroids is crucial for understanding the formation and degradation mechanisms at work on their surfaces. Using images and therma...
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Article
Open AccessAPOE*E2 allele delays age of onset in PSEN1 E280A Alzheimer’s disease
Alzheimer’s disease (AD) age of onset (ADAOO) varies greatly between individuals, with unique causal mutations suggesting the role of modifying genetic and environmental interactions. We analyzed ~50 000 commo...
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Article
Open AccessFagerstrom test for nicotine dependence vs heavy smoking index in a general population survey
The Fagerström Test for Nicotine Dependence (FTND) is used for assessing nicotine dependence. A shorter test derived from the FTND used for the general population is the Heavy Smoking Index (HSI) (six question...
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Article
Pharmacogenetics and pharmacogenomics of schizophrenia: a review of last decade of research
The last decade of research into the pharmacogenetics of antipsychotics has seen the development of genetic tests to determine the patients’ metabolic status and the first attempts at personalization of antips...
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Article
Physiogenomic comparison of weight profiles of olanzapine- and risperidone-treated patients
Atypical antipsychotics induce pre-diabetic symptoms in some but not all patients, characterized most notably by elevated weight. The side effect profiles of the various drugs in the class differ, however, rai...
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Article
CYP2D6 genetic variation in healthy adults and psychiatric African-American subjects: implications for clinical practice and genetic testing
Limited information is available on the frequency of the many CYP2D6 alleles found in African-Americans. DNA was isolated and genetic testing was performed on samples from 222 African-Americans, healthy controls ...
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Article
Dust Activity in Comet 67P/Churyumov–Gerasimenko from February 20 to April 20, 2003
Broadband imaging of Comet 67P/Churyumov–Gerasimenko has provided more data on the characterisation of the target of the ESA Rosetta Mission. The comet monitoring between r h=2.37 and r ...
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Article
Pharmacogenomic testing: the cost factor
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Article
Diurnal and weekly variation of tardive dyskinesia measured by digital image processing
The diurnal and weekly variability of tardive dyskinesia (TD) was assessed instrumentally by digital image processing. Weekly assessments were obtained in ten patients over a 6-week period. In six of the ten p...
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Article
Oral tardive dyskinesia: validation of a measuring device using digital image processing
The present study was performed to investigate the reliability and validity of a new device for the assessment of oral dyskinesias by means of digital image processing. Twenty schizophrenic patients with tardi...
