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Article
A Factor associated with ‘Visking’ Tubing capable of Antagonizing Insulin
DURING the investigation of the insulin antagonism associated with human serum albumin1, ‘Visking’ tubing (Visking Corporation, Chicago, U.S.A,) was used for ultrafiltration and dialysis of protein solutions. The...
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Article
Second Annual Meeting of the European Association for the Study of Diabetes abstracts
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Article
The inheritance of essential diabetes mellitus from studies of the synalbumin insulin antagonist
Patients with essential diabetes including prediabetes have more synalbumin antagonism to insulin than normal subjects or patients with “pancreatic” diabetes, e.g. after pancreatectomy. Thus excessive synalbum...
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Article
Inhibition of glutathione reductase in diabetics and non-diabetics
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Article
Third Meeting of the Scandinavian Society for the Study of Diabetes Oslo, February 2–4, 1967 Abstracts
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Article
In vivo effects of the synalbumin insulin antagonist
Albumin prepared from serum of diabetic patients inhibits the effect of insulin on rat diaphragm muscle but not on their epididymal fat pads when injected intravenously to make a foreign protein concentration ...
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Chapter
Insulin in Blood — The Antagonists
When considering the mechanisms concerned in the regulation of the blood glucose level, it becomes apparent that whereas only exercise or insulin will lower blood sugar there are a variety of factors and hormo...
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Article
Variations in synalbumin insulin antagonism during tolbutamide tolerance test
Albumin was extracted from plasma and serum taken during intravenous Tolbutamide tolerance tests in 18 healthy volunteers and tested at a concentration of 2.5 g per 100 ml for insulin antagonism. A significant...
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Article
Further studies on the incidence of the synalbumin insulin antagonist
The incidence of excessive synalbumin antagonism has been studied in a small randomly selected population survey. One hundred and forty-two volunteers were tested, 70 men and 72 women, between the ages of 18 a...
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Article
Arterial lipid metabolism in relation, to blood glucose and plasma insulin in rats with streptozotocin-induced diabetes
D-glucose-U-14C incorporation into arterial lipidsin vitro was greater (p<0.025) in control than in streptozotocin-treated (65 mg/kg) rats. A significant positive correlation between this effect and the plasma im...
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Article
Modern concepts of diabetes and its management
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Article
Precipitin reactions between insulin, proinsulin, insulin chains and insulin antibody
Insulin antibody was produced in guinea pigs and the precipitins tested by double diffusion in agarose gel. Pork, beef and monocomponent insulin produced precipitin lines. Proinsulin also produced a precipitin...
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Article
Spontaneous hypoglycaemia and diabetes mellitus
A CASE is reported of a man who, following partial gastrectomy in 1950, developed severe hypoglycaemic attacks. For this he had a distal pancreatectomy in 1966, when the islets were found to be increased in si...
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Article
Hepatic degradation of insulin and the release of its component A and B chains
This study confirms that insulin is degraded in the liver, that the immediate degradation products are its A and B chains, and that these are released to the circulation. The study also shows that the A and B ...
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Article
Book reviews
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Article
The prevalence of diabetes mellitus and an assessment of methods of detection among a community of elderly Chinese in Hong Kong
This study provides information on the prevalence of diabetes mellitus in a group of elderly Chinese subjects aged 60 and above living in the community in Hong Kong, and investigates the sensitivity of the uri...
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Chapter and Conference Paper
Nifedipine Retard as Monotherapy for Essential Hypertension: A Randomized Controlled Cross-over Study
Over the past couple of decades diuretics, methyldopa, and β-blockers have been the common drugs used as first-line regimen for treating hypertension [1–3]. Some large-scale long-term studies, however, have un...