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  1. No Access

    Chapter and Conference Paper

    Nifedipine Retard as Monotherapy for Essential Hypertension: A Randomized Controlled Cross-over Study

    Over the past couple of decades diuretics, methyldopa, and β-blockers have been the common drugs used as first-line regimen for treating hypertension [1–3]. Some large-scale long-term studies, however, have un...

    K. S. Woo, C. O. Pun, J. Vallance-Owen in Adalat® in the Asian Pacific Region (1989)

  2. Article

    The prevalence of diabetes mellitus and an assessment of methods of detection among a community of elderly Chinese in Hong Kong

    This study provides information on the prevalence of diabetes mellitus in a group of elderly Chinese subjects aged 60 and above living in the community in Hong Kong, and investigates the sensitivity of the uri...

    J. Woo, R. Swaminathan, C. Cockram, C. P. Pang, Y. T. Mak, S. Y. Au in Diabetologia (1987)

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    Article

    Book reviews

    B. M. Stokes, D. M. Mitchell, J. Vallance-owen in Irish Journal of Medical Science (1976)

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    Article

    Hepatic degradation of insulin and the release of its component A and B chains

    This study confirms that insulin is degraded in the liver, that the immediate degradation products are its A and B chains, and that these are released to the circulation. The study also shows that the A and B ...

    D. D. Bansal, J. S. Bajaj, Dorothy McMaster in Irish Journal of Medical Science (1975)

  5. No Access

    Article

    Spontaneous hypoglycaemia and diabetes mellitus

    A CASE is reported of a man who, following partial gastrectomy in 1950, developed severe hypoglycaemic attacks. For this he had a distal pancreatectomy in 1966, when the islets were found to be increased in si...

    J. Vallance-Owen, J. D. A. Robb in Irish Journal of Medical Science (1974)

  6. Article

    Precipitin reactions between insulin, proinsulin, insulin chains and insulin antibody

    Insulin antibody was produced in guinea pigs and the precipitins tested by double diffusion in agarose gel. Pork, beef and monocomponent insulin produced precipitin lines. Proinsulin also produced a precipitin...

    D. D. Bansal, J. H. Connolly, J. Vallance-Owen in Diabetologia (1973)

  7. No Access

    Article

    Modern concepts of diabetes and its management

    J. Vallance-Owen in Irish Journal of Medical Science (1973)

  8. Article

    Arterial lipid metabolism in relation, to blood glucose and plasma insulin in rats with streptozotocin-induced diabetes

    D-glucose-U-14C incorporation into arterial lipidsin vitro was greater (p<0.025) in control than in streptozotocin-treated (65 mg/kg) rats. A significant positive correlation between this effect and the plasma im...

    R. W. Stout, K. D. Buchanan, J. Vallance-Owen in Diabetologia (1972)

  9. Article

    Variations in synalbumin insulin antagonism during tolbutamide tolerance test

    Albumin was extracted from plasma and serum taken during intravenous Tolbutamide tolerance tests in 18 healthy volunteers and tested at a concentration of 2.5 g per 100 ml for insulin antagonism. A significant...

    J. S. Bajaj, J. Vallance-Owen in Diabetologia (1971)

  10. Article

    Further studies on the incidence of the synalbumin insulin antagonist

    The incidence of excessive synalbumin antagonism has been studied in a small randomly selected population survey. One hundred and forty-two volunteers were tested, 70 men and 72 women, between the ages of 18 a...

    J. S. Bajaj, D. McMaster, J. Vallance-Owen in Diabetologia (1971)

  11. No Access

    Chapter

    Insulin in Blood — The Antagonists

    When considering the mechanisms concerned in the regulation of the blood glucose level, it becomes apparent that whereas only exercise or insulin will lower blood sugar there are a variety of factors and hormo...

    J. Vallance-Owen in Pathophysiologie und Klinik / Pathophysiol… (1971)

  12. Article

    In vivo effects of the synalbumin insulin antagonist

    Albumin prepared from serum of diabetic patients inhibits the effect of insulin on rat diaphragm muscle but not on their epididymal fat pads when injected intravenously to make a foreign protein concentration ...

    L. Kammerer, J. Vallance-Owen in Diabetologia (1968)

  13. No Access

    Article

    Third Meeting of the Scandinavian Society for the Study of Diabetes Oslo, February 2–4, 1967 Abstracts

    Jacob E. Poulsen, Rolf Luft, O. Trygstad, Erol Cerasi, Hans Yde in Diabetologia (1967)

  14. Article

    Inhibition of glutathione reductase in diabetics and non-diabetics

    J. Jervell, J. Vallance-Owen in Diabetologia (1967)

  15. Article

    The inheritance of essential diabetes mellitus from studies of the synalbumin insulin antagonist

    Patients with essential diabetes including prediabetes have more synalbumin antagonism to insulin than normal subjects or patients with “pancreatic” diabetes, e.g. after pancreatectomy. Thus excessive synalbum...

    J. Vallance-Owen in Diabetologia (1966)

  16. No Access

    Article

    Second Annual Meeting of the European Association for the Study of Diabetes abstracts

    J. T. Ireland, B. K. Patnaik, L. J. P. Duncan, Z. Jaksic, A. Jakob in Diabetologia (1966)

  17. No Access

    Article

    A Factor associated with ‘Visking’ Tubing capable of Antagonizing Insulin

    DURING the investigation of the insulin antagonism associated with human serum albumin1, ‘Visking’ tubing (Visking Corporation, Chicago, U.S.A,) was used for ultrafiltration and dialysis of protein solutions. The...

    M. DELORIS LILLEY, J. VALLANCE-OWEN in Nature (1961)