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Article
Open AccessEffects of running on adiponectin, insulin and cytokines in cerebrospinal fluid in healthy young individuals
Exercise can prevent the sedentary lifestyle-related risk of metabolic and cognitive decline, but mechanisms and mediators of exercise effects on human brain are relatively unexplored. We measured acute exerci...
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Article
Prior Repeated Stress Attenuates Cold-Induced Immunomodulation Associated with “Browning” in Mesenteric Fat of Rats
Continuous exposure to cold leads to activation of adaptive thermogenesis in brown adipose tissue but also to induction of brown/beige cell phenotype in white adipose tissue. The aim of this work was to invest...
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Article
Open AccessBCR-ABL1 mutation development during first-line treatment with dasatinib or imatinib for chronic myeloid leukemia in chronic phase
BCR-ABL1 mutations are a common, well-characterized mechanism of resistance to imatinib as first-line treatment of chronic myeloid leukemia in chronic phase (CML-CP). Less is known about mutation development duri...
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Article
Effects of Hypoxia on Adipose Tissue Expression of NFκB, IκBα, IKKγ and IKAP in Patients with Chronic Obstructive Pulmonary Disease
Recently we observed increased adipose tissue (AT) expression of CD40-related signaling proteins but no activation of tumor necrosis factor-α or CD68 in patients with chronic sustained hypoxia resulting from c...
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Article
Stress Stimulates Production of Catecholamines in Rat Adipocytes
The sympathoadrenal system is the main source of catecholamines (CAs) in adipose tissues and therefore plays the key role in the regulation of adipose tissue metabolism. We recently reported existence of an al...
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Article
High prevalence of prediabetes and diabetes in a population exposed to high levels of an organochlorine cocktail
A heavily polluted area of Eastern Slovakia was targeted by the PCBRISK cross-sectional survey to search for possible links between environmental pollution and both prediabetes and diabetes.
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40th EASD Annual Meeting of the European Association for the Study of Diabetes
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The hypotriglyceridemic effect of dietary n−3 FA is associated with increased β-oxidation and reduced leptin expression
To study the mechanisms responsible for the hypotriglyceridemic effect of marine oils, we monitored the effects of high dietary intake of n−3 PUFA on hepatic and muscular β-oxidation, plasma leptin concentrati...
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35th Annual Meeting of the European Association for the Study of Diabetes