4 Result(s)

Article

Regulation of GAD expression in rat pancreatic islets and brain by γ-vinyl-GABA and glucose

Glutamic acid decarboxylase (GAD) is an important autoantigen in insulin-dependent diabetes mellitus (IDDM), but little is known about its regulation and function in islet cells. We investigated the effects o...

J. S. Petersen, K. Rimvall, P. N. Jørgensen, E. Hasselager, A. Moody… in Diabetologia (1998)

Article

A novel inhibitor of advanced glycation end-product formation inhibits mesenteric vascular hypertrophy in experimental diabetes

Aims/hypothesis. Previous studies in our laboratory have shown that the vascular changes in diabetes include hypertrophy of the mesenteric vasculature and that this process can be attenuated by t...

T. Soulis, S. Sastra, V. Thallas, S. B. Mortensen, M. Wilken, J. T. Clausen… in Diabetologia (1999)

Article

Differential accumulation of advanced glycation end products in the course of diabetic retinopathy

Aims/hypothesis. Glycated proteins, formed by reaction of glucose and protein, react further yielding numerous, mostly undefined advanced glycation end products (AGE). The recently characterized ...

H.-P. Hammes, A. Alt, T. Niwa, J. T. Clausen, R. G. Bretzel, M. Brownlee… in Diabetologia (1999)

Article

35th Annual Meeting of the European Association for the Study of Diabetes

A. Melander, J. Olsson, G. Lindberg, A. Salzman, T. Howard, P. Stang… in Diabetologia (1999)