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  1. Article

    Open Access

    The effect of chemotherapy on health-related quality of life in mesothelioma: results from the SWAMP trial

    The effect of chemotherapy on health-related quality of life (HRQoL) in malignant pleural mesothelioma (MPM) is poorly understood. Patient-individualised prognostication and prediction of treatment response fr...

    D T Arnold, C E Hooper, A Morley, P White, I D Lyburn… in British Journal of Cancer (2015)

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  2. Article

    Open Access

    The South West Area Mesothelioma and Pemetrexed trial: a multicentre prospective observational study evaluating novel markers of chemotherapy response and prognostication

    Robust markers that predict prognosis and detect early treatment response in malignant pleural mesothelioma (MPM) would enhance patient care.

    C E Hooper, I D Lyburn, J Searle, M Darby, T Hall, D Hall… in British Journal of Cancer (2015)

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  3. No Access

    Article

    Colorectal carcinomas show frequent allelic loss on the long arm of chromosome 17 with evidence for a specific target region

    Allelic loss is a common mechanism of inactivation of tumour-suppressor genes in colorectal carcinomas. A number of known or putative tumour-suppressor genes including NF1, BRCA1, NME1, NME2 and prohibitin are...

    B Leggett, J Young, R Buttenshaw, L Thomas, B Young… in British Journal of Cancer (1995)

  4. No Access

    Article

    Loss of heterozygosity on the long arm of chromosome 11 in colorectal tumours

    We have examined a series of human colorectal adenomas, carcinomas and cell lines derived from human colorectal cancer for loss of heterozygosity (LOH) on chromosome 11q22-23 by polymerase chain reaction (PCR)...

    CE Gustafson, J Young, B Leggett, J Searle, G Chenevix-Trench in British Journal of Cancer (1994)