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    Article

    Estrogen-dependent sushi domain containing 3 regulates cytoskeleton organization and migration in breast cancer cells

    Aromatase inhibitors (AIs) are the standard endocrine therapy for postmenopausal breast cancer; however, currently used biomarkers, such as, estrogen receptor-alpha/progesterone receptor (ERα/PR), predict only...

    I Moy, V Todorović, A D Dubash, J S Coon, J B Parker, M Buranapramest in Oncogene (2015)

  2. Article

    Ligand-Activated Peroxisome Proliferator-Activated Receptor β/δ Modulates Human Endometrial Cancer Cell Survival

    Endometrial cancer is the fourth most common malignancy among women and is a major cause of morbidity contributing to approximately 8,200 annual deaths in the USA. Despite advances to the understanding of endo...

    J. J. Ma, D. Monsivais, M. T. Dyson, J. S. Coon, S. Malpani, M. Ono in Hormones and Cancer (2013)

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    Knockdown of splicing factor SRp20 causes apoptosis in ovarian cancer cells and its expression is associated with malignancy of epithelial ovarian cancer

    Our previous study revealed that two splicing factors, polypyrimidine tract-binding protein (PTB) and SRp20, were upregulated in epithelial ovarian cancer (EOC) and knockdown of PTB expression inhibited ovaria...

    X He, A D Arslan, M D Pool, T-T Ho, K M Darcy, J S Coon, W T Beck in Oncogene (2011)

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    Article

    Knockdown of polypyrimidine tract-binding protein suppresses ovarian tumor cell growth and invasiveness in vitro

    Polypyrimidine tract-binding protein (PTB) is an RNA-binding protein with multiple functions in the regulation of RNA processing and IRES-mediated translation. We report here overexpression of PTB in a majorit...

    X He, M Pool, K M Darcy, S B Lim, N Auersperg, J S Coon, W T Beck in Oncogene (2007)