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Chapter
Stoffwechselnotfälle
haben einen kleineren Anteil am Gesamtkollektiv, können jedoch mit Bewusstseinsstörungen einhergehen und müssen daher häufig in die differenzialdiagnostischen Überlegungen mit einbezogen werden.
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Chapter
Generation of Immunoglobulin/c-myc Recombinations in Murine Peyer’s Patch Follicles
Plasmacytoma can be induced by the intraperitoneal injection of pristane in susceptible BALB/c mice. Most inbred strains of mice, however, are resistant to this type of plasmacytoma induction (Potter & Wiener,...
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Chapter
Genetic Recombinations Between c-myc and Ighμ as Precursors for Recombinations Between c-myc and Ighα in BALB/c Plasmacytomas
In this paper we present evidence that primary plasmacytomas harboring a balanced chromosomal translocation t(12;15) may consist of a mosaic of neoplastic clones of tumor cells, in which some of the clones are...
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Chapter
Genomic Instability in B-Cells and Diversity of Recombinations That Activate c-myc
Genetic rearrangements activating the proto-oncogene c-myc comprise a mandatory oncogenic step in plasma cell tumor development in BALB/cAnPt mice. In the majority of plasmacytomas, c-myc activating rearrangement...
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Chapter
Illegitimate Recombinations Between c-myc and Immunoglobulin Loci are Remodeled by Deletions in Mouse Plasmacytomas but not in Burkitt’s Lymphomas
Recombinations between c-myc and immunoglobulin loci are a hallmark of Burkitt’s lymphomas and mouse plasmacytomas. Analyzing the fine structure of these illegitimate rearrangements has revealed differences betwe...