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  1. Article

    Open Access

    Genetic and metabolic predictors of chemosensitivity in oligodendroglial neoplasms

    The −1p/−19q genotype predicts chemosensitivity in oligodendroglial neoplasms, but some with intact 1p/19q also respond and not all with 1p/19q loss derive durable benefit from chemotherapy. We have evaluated ...

    C Walker, B Haylock, D Husband, K A Joyce, D Fildes… in British Journal of Cancer (2006)

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    Article

    Degeneracy in human multicopy RBM (YRRM), a candidate spermatogenesis gene

    In order to search for mutations in the multicopy RBM genes that might be associated with male infertility, we have used sequence data from the reported cDNA clone to determine the intron exon boundaries of th...

    J. Prosser, J. D. Inglis, A. Condie, K. Ma, S. Kerr, R. Thakrar… in Mammalian Genome (1996)

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    Article

    APC mutation analysis by chemical cleavage of mismatch and a protein truncation assay in familial adenomatous polyposis

    Overall, the causative APC mutation has been identified in only 30% of the patients with familial adenomatous polyposis (FAP) who have been included in studies reported in the literature. In order to determine...

    J Prosser, A Condie, M Wright, JM Horn, JA Fantes, AH Wyllie… in British Journal of Cancer (1994)

  4. No Access

    Article

    Exclusion of constitutional p53 mutations as a cause of genetic susceptibility to colorectal cancer

    T Bhagirath, A Condie, MG Dunlop, AH Wyllie, J Prosser in British Journal of Cancer (1993)

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    Article

    Constitutional p53 mutation in a non-Li-Fraumeni cancer family

    J Prosser, D Porter, C Coles, A Condie, AM Thompson, U Chetty… in British Journal of Cancer (1992)

  6. No Access

    Article

    Mutations in p53 do not account for heritable breast cancer: a study in five affected families

    J Prosser, PA Elder, A Condie, I MacFadyen, CM Steel, HJ Evans in British Journal of Cancer (1991)

  7. No Access

    Article

    The chromosomal localisation of human satellite DNA I

    The major concentrations of human satellite DNA I (1.688 g/ml) have been localised on human chromosome preparations by the technique of in situ hybridisation using radioactive complementary RNA synthesised in vit...

    K. W. Jones, I. F. Purdom, J. Prosser, G. Corneo in Chromosoma (1974)

  8. No Access

    Article

    The chromosomal location of human satellite DNA III

    In situ hybridisation of radioactive complementary RNA has been used to localise the chromosomal distribution of human satellite DNA III. This DNA is found to be concentrated in paracentromeric heterochromatin m...

    K. W. Jones, J. Prosser, G. Corneo, E. Ginelli in Chromosoma (1973)