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Article
Open AccessSurgical management of chest injuries in patients with multiple and/or severe trauma– a systematic review and clinical practice guideline update
Our aim was to update evidence-based and consensus-based recommendations for the surgical and interventional management of blunt or penetrating injuries to the chest in patients with multiple and/or severe inj...
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Article
Evaluation zur Infrastruktur für klinisch chirurgische Studien in Deutschland
Um die Qualität und Quantität klinischer Studien in der Chirurgie zu verbessern, wurde mithilfe einer Förderung durch das Bundesministerium für Bildung und Forschung (BMBF) das chirurgische Studiennetzwerk CHIR-N...
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Chapter
Management des Spontanpneumothorax
Der primäre Spontanpneumothorax (PSP) tritt überwiegend bei gesunden Männern unter 30 Jahren auf. Die Symptomatik reicht vom radiologischen Zufallsbefund ohne Beschwerden bis hin zur akuten Lebensgefahr. In de...
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Article
Evidenzlage der laparoskopischen Chirurgie beim Kolonkarzinom
Die Entwicklung videoendoskopischer Techniken erlaubt die minimal-invasive Resektion von Kolonkarzinomen.
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Article
Evidenzlage der laparoskopischen Chirurgie beim Kolonkarzinom
Die Entwicklung videoendoskopischer Techniken erlaubt die minimal-invasive Resektion von Kolonkarzinomen.
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Article
Warum Schwestern fliegen und Ärzte rotieren
Das chirurgische Studiennetzwerk (CHIR-Net) besteht aus acht chirurgischen Regionalzentren und wird seit 2006 durch das BMBF gefördert (Förderkennzeichen: 01GH1001A–01GH1001F, 01GH0702). Ziel des Netzwerkes is...
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Article
Klinische Studien außerhalb von Universitätskliniken
Die Forderung nach hochwertiger evidenzbasierter Therapie in der operativen Medizin in Deutschland und das Bewusstsein über die meist erheblich mangelhafte Qualität der chirurgischen Studien macht die Notwendi...
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Article
Hyaluronan levels during laparoscopic versus open colonic resections
Plasma hyaluronan binds to fibrinogen, affecting intravascular fibrin polymerization and fibrin clot formation. It has been hypothesized that alterations in fibrin clot formation influence the risk of thromboe...
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Chapter and Conference Paper
Kurzfristige Ergebnisse nach laparoskopischen oder konventionellen Resektionen von kolorektalen Karzinomen — Ergebnisse der randomisierten, kontrollierten, multizentrischen LAPKON II-Studie
Background: Elective laparoscopic colorectal resection is technically feasible in benign disease as well as colorectal cancer and functional short-term benefits of the laparoscopic approach to co...
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Article
“Fast-track” rehabilitation after rectal cancer resection
After rectal cancer surgery, postoperative general complications occur in 25–35% of all patients and postoperative hospital stay is 14–21 days. “Fast-track” rehabilitation has been shown to accelerate recovery...
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Article
Systematic evaluation of different approaches for minimizing hemodynamic changes during pneumoperitoneum
Capnoperitoneum (CP) compromises hemodynamic function during laparoscopy. Three therapeutic concepts were evaluated with an aim to minimize the hemodynamic reaction to CP: First, a controlled increase of intra...
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Article
Reply to the letter by M. Nagelschmidt regarding our article “Fibrinolytic capacity in peritoneal fluid after laparoscopic and conventional colorectal resection: data from a randomized controlled trial”
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Chapter and Conference Paper
Methodologische Qualität randomisierter, kontrollierter Studien in der laparoskopischen kolorektalen Chirurgie. Ergebnisse des systematischen Cochrane-Reviews
Randomisierten, kontrollierten Studien und systematischen Reviews von RCT wird heute das höchste Level wissenschaftlicher Evidenz zugewiesen. Unabhängig von dieser Tatsache müssen aber auch diese Studien immer...
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Article
Fibrinolytic capacity in peritoneal fluid after laparoscopic and conventional colorectal resection: data from a randomized controlled trial
A reduced peritoneal fibrinolytic capacity after surgery is currently accepted to be the main cause for postoperative adhesions. The aim of this prospective randomized trial was to determine the fibrinolytic a...
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Article
Comparison of EORTC Quality of Life Core Questionnaire (EORTC-QLQ-C30) and Gastrointestinal Quality of Life Index (GIQLI) in patients undergoing elective colorectal cancer resection
EORTC-QLQ-C30 questionnaires and GIQLI questionnaires are used to evaluate post-operative quality of life (QoL). It was not clear whether results of both instruments are comparable. Therefore, the level of agr...
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Article
Prospective randomized trial to determine the influence of laparoscopic and conventional colorectal resection on intravasal fibrinolytic capacity
Background: Although the pneumoperitoneum decreases venous reflux from the lower extremities, the rate of thromboembolic complcations seems to be lower after laparoscopic than after conventional procedures. Th...
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Article
Effect of laparoscopic and conventional colorectal resection on peritoneal fibrinolytic capacity: a prospective randomized clinical trial
Background and aims: Reduced fibrinolytic activity of the peritoneum seems to be the main cause of postoperative adhesions. This prospective randomized trial compared the peritoneal fibrinolytic ...
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Article
The European Association for Endoscopic Surgery clinical practice guideline on the pneumoperitoneum for laparoscopic surgery
Background: The pneumoperitoneum is the crucial element in laparoscopic surgery. Different clinical problems are associated with this procedure, which has led to various modifications of the technique. The aim...
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Chapter and Conference Paper
Ist die intravasale Fibrinolyse bei laparoskopischen kolorektalen Resektionen erhöht?
Der durch ein Pneumoperitoneum erhöhte intraabdominelle Druck vermindert den venösen Rückstrom, führt zu einer venösen Stase in den unteren Extremitäten und erhöht das Risiko thromboembolischer Komplikationen....
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Article
Prospective randomized blinded trial of pulmonary function, pain, and cosmetic results after laparoscopic vs microlaparoscopic cholecystectomy
Background: The size of laparoscopic instruments has been reduced for use in abdominal video endoscopic surgery. However, it has yet to be proven that microlaparoscopic surgery will actually resu...
