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Chapter
Map** and Analysis of Receptors for Neurohypophyseal Peptides Present in the Brain
Vasopressin (AVP) and oxytocin (OT) meet most of the criteria which are usually applied to assign a role as a neurotransmitter or neuromodulator to a given compound. 1) In addition to their presence in the hyp...
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Chapter and Conference Paper
Excitatory Effects of Substance P and Related Peptides on Oxytocin-Sensitive Non-Pyramidal Neurones in Rat Hippocampus
Substance P, eledoisin and physalaemin are undecapeptides that share a common C terminus amino acid sequence and therefore belong to the tachykinin family. The rat hippocampus contains scattered substance P im...
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Chapter
Oxytocin and Vasopressin
Toward the end of the 19th century, the functions of most endocrine glands were revealed by a combination of surgical removal and of injection of crude extracts. In particular, the intravenous injection of a c...
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Article
Vasopressin excites hippocampal neurones
Hypothalmic supraoptic and paraventricular neurones were the first peptidergic cells to be described in the mammalian brain1. Most of these large nerve cells synthesize either oxytocin or vasopressin2, as well as...
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Article
Paraventricular neurones in the rat hypothalamic slice: Lucifer Yellow injection and immunocytochemical identification
Intracellular records were obtained from paraventricular neurones injected with Lucifer Yellow in slices from the rat hypothalamus. Slices containing fluorescent neurones were then serially cut and alternating...
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Article
Calcium-dependent somatostatin secretion from rat neurohypophysis in vitro
THE tetradecapeptide somatostatin originally identified in hypothalamic extracts, has been subsequently shown by bioassay, radioimmunoassay and immunohistochemical techniques to be extensively distributed thro...
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Article
Ultrastructural identification of granules containing oxytocin and vasopressin
OXYTOCIN and vasopressin, the hormones of the mammalian hypothalamo–neurohypophysial complex, are synthesised in the supraoptic (SON) and paraventricular (PVN) nuclei and are secreted into the blood stream fro...
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Article
Specific arrangements of membrane particles at sites of exo-endocytosis in the freeze-etched neurohypophysis
Images have been obtained from freeze-etch replicas of neurohypophyses which are consistent with the view that orderly arranged aggregates of membrane particles occur in regions where fragments of membrane are...
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Article
Excitation of phasically firing supraoptic neurones during vasopressin release
THE neurohypophysial hormones vasopressin and oxytocin are synthesised within separate neurones of the hypothalamic supraoptic and paraventricular nuclei1 and each hormone can be liberated independently. Haemorrh...
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Article
Ultrastructural evidence for sinusoid spaces and coupling between pituicytes in the rat
The pericapillary palisade of the rat neurohypophysis was examined by means of thin-section and freeze-etch electron-microscopy. Special attention was given to pituicyte processes intermingled with neurosecret...
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Article
Water deprivation in rats: Elevated plasma neurophysin levels
Au cours de la privation d'eau potabel chez le rat, on observe une diminution du contenu en ocytocine, vasopressine et neurophysine immunoréactives du lobe postérieur de l'hypophyse et une augmentation du taux...
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Article
Secretion-dependent uptake of extracellular fluid by the rat neurohypophysis
THERE is considerable evidence that hormone secretion from the neurohypophysis occurs by exocytosis of neurosecretory granules present in the nerve terminals1–4. Exocytosis involves fusion of the granule membrane...
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Chapter
Exo-Endocytosis in the Neurohypophysis as Revealed by Freeze-Fracturing
Evidence has accumulated to indicate that the release of the neurohypophysial hormones occurs by exocytosis (emiocytosis, and reverse pinocytosis, are synonyms). During this process, the secretory granule-limi...
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Chapter
Do Hypothalamic Neuroendocrine Cells Have a Synaptic Output?
The main problems concerning the synthesis of vasopressin and oxytocin in the cell bodies of the supraoptic and paraventricular nuclei of the hypothalamus, the axonal transport of the neurosecretory material t...
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Chapter
Effects of Electrical Stimulation of the Amygdaloid Complex on the Ventromedial Hypothalamus
The basal hypothalamus serves as a primary control region for a multitude of visceral regulatory mechanisms essential for the organism, such as the regulation of temperature (Hammel, 1968), feeding behavior (S...
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Article
A correlation of release of polypeptide hormones and of immunoreactive neurophysin from isolated rat neurohypophyses
La stimulation électrique de neurophypophyses de rat in vitro provoque la libération conjointe d'hormones et de neurophysine. Cette observation suggère que la secrétion neurohormonale implique l'extrusion du c...
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Article
Antagonism between Ca and Na ions at neurohypophysial nerve terminals
La secrétion hormonale de neurohypophyses isolées de rat a été estimée à l'aide d'un test d'éjection du lait. Au moment de la dépolarisation des terminaisons neurosecrétrices, il y a compétition entre le sodiu...
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Chapter
Absence of Measurable Amounts of Epinephrine, Norepinephrine and Dopamine in Rat Hypophysial Portal Blood during Various Phases of the Oestrous Cycle
Fluorescence techniques were used for the estimation of epinephrine, dopamine and norepinephrine in hypophysial portal vein blood of rats. The techniques employed allow the detection of norepinephrine and dopa...
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Article
Union Schweizerischer Gesellschaften für experimentelle Biologie Berichte der 2. Jahresversammlung
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Article
Cortical inhibition and γ-aminobutyric acid
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In cats under Dial, multiple micro-electrodes were used to analyze the changes in membrane potential and cond...
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