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Article
Open AccessDevelopment of a Prediction Model for Antibiotic-Resistant Urinary Tract Infections Using Integrated Electronic Health Records from Multiple Clinics in North-Central Florida
Urinary tract infections (UTIs) are common infections for which initial antibiotic treatment decisions are empirically based, often without antibiotic susceptibility testing to evaluate resistance, increasing ...
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Article
Open AccessIndependent infections of porcine deltacoronavirus among Haitian children
Coronaviruses have caused three major epidemics since 2003, including the ongoing SARS-CoV-2 pandemic. In each case, the emergence of coronavirus in our species has been associated with zoonotic transmissions ...
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Article
Activation of Vibrio cholerae quorum sensing promotes survival of an arthropod host
Vibrio cholerae colonizes the human terminal ileum to cause cholera, and the arthropod intestine and exoskeleton to persist in the aquatic environment. Attachment to these surfaces is regulated b...
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Article
Open AccessIndicators of anemia and physical growth in schoolchildren from the Ouest and Sud-Est Departments of Haiti: a cross-sectional study
The identification and correction of malnutrition in children remains a critical public health issue in many develo** countries. In this study, the rate of anemia and standardized indicators of physical grow...
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Article
Feasibility of the hydrogen sulfide test for the assessment of drinking water quality in post-earthquake Haiti
In 2010, a magnitude 7.0 earthquake struck Haiti, severely damaging the drinking and wastewater infrastructure and leaving millions homeless. Compounding this problem, the introduction of Vibrio cholerae resulted...
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Chapter
Circulation and Transmission of Clones of Vibrio cholerae During Cholera Outbreaks
Cholera is still a major public health problem. The underlying bacterial pathogen Vibrio cholerae (V. cholerae) is evolving and some of its mutations have set the stage for outbreaks. After V. cholerae acquired t...
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Chapter
Modeling Cholera Outbreaks
Mathematical modeling can be a valuable tool for studying infectious disease outbreak dynamics and simulating the effects of possible interventions. Here, we describe approaches to modeling cholera outbreaks a...
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Article
Open AccessMolecular Epidemiology of Community-Associated Methicillin-resistant Staphylococcus aureus in the genomic era: a Cross-Sectional Study
Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of healthcare-associated infections and significant contributor to healthcare cost. Community-associated-MRSA (CA-MRSA) strains have now invad...
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Article
Open AccessA ubiquitous method for street scale spatial data collection and analysis in challenging urban environments: map** health risks using spatial video in Haiti
Fine-scale and longitudinal geospatial analysis of health risks in challenging urban areas is often limited by the lack of other spatial layers even if case data are available. Underlying population counts, re...
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Article
Open AccessCholera in Haiti: Reproductive numbers and vaccination coverage estimates
Cholera reappeared in Haiti in October, 2010 after decades of absence. Cases were first detected in Artibonite region and in the ensuing months the disease spread to every department in the country. The rate o...
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Article
Open AccessGenetic analysis of the capsule polysaccharide (K antigen) and exopolysaccharide genes in pandemic Vibrio parahaemolyticus O3:K6
Pandemic Vibrio parahaemolyticus has undergone rapid changes in both K- and O-antigens, making detection of outbreaks more difficult. In order to understand these rapid changes, the genetic regions encoding these...
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Chapter and Conference Paper
Global Effect and Prevention of Emerging and Epidemic Pathogens: Cholera and Citrus Greening as Examples
Emerging and epidemic infectious diseases have had a major effect on human history. We are just now coming to appreciate the mechanisms by which new strains emerge and the factors that permit their rapid sprea...
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Article
Cholera transmission: the host, pathogen and bacteriophage dynamic
Vibrio cholerae is a facultative pathogen that has an environmental reservoir in aquatic ecosystems and a pathogenic phase in the human small intestine. It pro...
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Chapter
Bacterial Foodborne Disease
Foodborne disease comprises a broad group of illnesses caused by the consumption of foods contaminated with toxic substances or pathogenic microorganisms. The agents responsible for foodborne illnesses can be ...
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Chapter
Bacterial Foodborne Disease
Foodborne disease comprises a broad group of illnesses caused by the consumption of foods contaminated with toxic substances or pathogenic microorganisms. The agents responsible for foodborne illnesses can be ...
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Article
Escherichia coli Transcytosis in a Caco-2 Cell Model: Implications in Neonatal Necrotizing Enterocolitis
Necrotizing enterocolitis (NEC) is a serious gastrointestinal disorder of preterm infants. Other than an association with prematurity and gastrointestinal feeding, no single factor or mechanism has been consis...
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Article
Occurrence of Necrotizing Enterocolitis May Be Dependent on Patterns of Bacterial Adherence and Intestinal Colonization: Studies in Caco-2 Tissue Culture and Weanling Rabbit Models
ABSTRACT: Necrotizing enterocolitis (NEC) is one of the leading causes of death in neonatal intensive care units. The underlying pathophysiology of NEC is poorly defined, although there is a suggestion that ba...
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Article
ENTERIC ADENOVIRUS AS A CAUSE OF OUTPATIENT DIARRHEA IN BALTIMORE CHILDREN
Enteric adenoviruses (EA) are a recently described cause of diarrhea in hospitalized children, but the incidence in outpatients with less severe diarrhea is not well documented. In a 1 year prospective study o...