-
Article
Assessment of panobacumab as adjunctive immunotherapy for the treatment of nosocomial Pseudomonas aeruginosa pneumonia
The fully human anti-lipopolysaccharide (LPS) immunoglobulin M (IgM) monoclonal antibody panobacumab was developed as an adjunctive immunotherapy for the treatment of O11 serotype Pseudomonas aeruginosa infection...
-
Article
Posaconazole salvage treatment in paediatric patients: a multicentre survey
While a paediatric dosage has not been defined, posaconazole is occasionally being used in children. We conducted a multicentre retrospective survey and identified 15 patients (median age 10 years [range 3.6–1...
-
Article
Nocardiosis: Updated Clinical Review and Experience at a Tertiary Center
Nocardiosis is a rare opportunistic disease that affects mainly patients with deficient cell-mediated immunity, such as those with acquired immunodeficiency syndrome (AIDS) or transplant recipients. Pulmonary ...
-
Article
Candida parapsilosis endocarditis: a comparative review of the literature
Fungal endocarditis (FE) is an uncommon disease, and while accounting for only 1.3–6% of all cases of infectious endocarditis, it carries a high mortality risk. Although Candida albicans represents the main etiol...
-
Article
A Randomized Prospective Study of Cefepime Plus Metronidazole with Imipenem-Cilastatin in the Treatment of Intra-abdominal Infections
Presumptive antimicrobial therapy is an important aspect of the management of intra-abdominal infections. Together with surgery, antimicrobial combinations are still widely used to achieve the required spectru...
-
Article
Lack of effect of combination antibiotic therapy on mortality in patients with pneumococcal sepsis
In order to determine whether combination antibiotic therapy decreases mortality after severe pneumococcal infection, a retrospective study of a cohort of 1,840 adult patients with severe sepsis or septic shoc...
-
Article
Disseminated histoplasmosis in an HIV-infected patient discovered by routine blood smear staining
-
Article
Severe Mycoplasma hominis Infections in Two Renal Transplant Patients
Systemic infections due to Mycoplasma hominis are rare and occur mainly in immunocompromised patients. Reported here are the cases of two renal transplant patients with peritonitis who did not respond to empirica...
-
Article
Successful Treatment of Pulmonary Invasive Aspergillosis with Voriconazole in Patients who Failed Conventional Therapy
Background: The incidence of fungal infections, including those due to Aspergillosis species has continued to increase in recent years. Invasive aspergillosis remains an important cause of morbidity and mortalit...
-
Article
Frequency, mortality and risk factors of candidemia at a tertiary care hospital
-
Article
Enteral versus parenteral nutrition: no difference in the incidence of fungal infections in critically-ill patients on mechanical ventilation with selective digestive decontamination
-
Article
ARDS caused by herpes simplex virus pneumonia in a patient with Crohn's disease: a case report
Pneumonia caused by herpes simplex virus type 1 (HSV1) is rare and occurs in severely immunosuppressed patients. HSV1 can be detected in bronchoalveolar lavage (BAL) from patients presenting with respiratory ...
-
Article
Free Papers
-
Article
Influence of posture on gas exchange in artificially ventilated patients with focal lung disease
Six patients were artificially ventilated for a focal lung disease localized to one lung in four cases and to both lower lobes in two. Despite an inspired oxygen concentration of 100% the mean PaO2 was 115 mmHg. ...
