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Open AccessA randomized controlled trial to compare the effects of time-restricted eating versus Mediterranean diet on symptoms and quality of life in bipolar disorder
The primary objective of this randomized controlled trial (RCT) is to establish the effectiveness of time-restricted eating (TRE) compared with the Mediterranean diet for people with bipolar disorder (BD) who ...
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Open AccessFine-map** the immunodominant antibody epitopes on consensus sequence-based HIV-1 envelope trimer vaccine candidates
The HIV-1 envelope glycoprotein (Env) trimer is the key target for vaccines aimed at inducing neutralizing antibodies (NAbs) against HIV-1. The clinical candidate immunogen ConM SOSIP.v7 is a stabilized native...
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Optimization of excess system capability for increased evolvability
System evolvability is vital to the longevity of large-scale complex engineered systems. The need for evolvability in complex systems is a result of their long service lives, rapid advances to their integrated...
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Tobacco use among low-income housing residents: does hardship motivate quit attempts?
The purpose of this study was to examine material hardship among smokers to determine whether such hardship was positively associated with current attempts to quit tobacco use.
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Clinical validity: Combinatorial pharmacogenomics predicts antidepressant responses and healthcare utilizations better than single gene phenotypes
In four previous studies, a combinatorial multigene pharmacogenomic test (GeneSight) predicted those patients whose antidepressant treatment for major depressive disorder resulted in poorer efficacy and increa...
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Open AccessPsychiatric pharmacogenomics predicts health resource utilization of outpatients with anxiety and depression
Antidepressants are among the most widely prescribed medications, yet only 35–45% of patients achieve remission following an initial antidepressant trial. The financial burden of treatment failures in direct t...
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Open AccessUsing a pharmacogenomic algorithm to guide the treatment of depression
The objective of this study was to evaluate the potential benefit of utilizing a pharmacogenomic testing report to guide the selection and dosing of psychotropic medications in an outpatient psychiatric practi...
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1 Attenuation of Airway Responsiveness in Pak 1 KO Mice.
Pak 1 (p21-activated kinase) is involved in the regulation of airway smooth muscle (ASM) contraction in vitro. We hypothesized that the genetic disruption of Pak1 would attenuate in vivo airway responsiveness to ...
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Is Apaf-1 expression frequently abrogated in melanoma?
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Multidrug resistance genes in infant acute lymphoblastic leukemia: Ara-C is not a substrate for the breast cancer resistance protein
Infants with acute lymphoblastic leukemia (ALL) are more resistant to chemotherapeutic drugs than older children with ALL, except for Ara-C. Drug resistance mechanisms in infant ALL, however, remain unknown. P...
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Inhaled nitric oxide in combination with volume resuscitation refines a porcine model of endotoxic shock
Existing porcine models of endotoxic shock poorly represent the human situation.
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Irish endocrine society: 23rd annual meeting
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Irish cardiac society
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National scientific medical meeting 1995 abstracts
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Irish cardiac society Proceedings of Annual General Meeting held 4th/5th November, 1994
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National Scientific Medical Meeting 1994 Abstracts
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Irish Cardiac Society
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Royal Academy of Medicine in Ireland Section of Biomedical Sciences Proceedings of Summer Meeting held 22nd & 23rd June, 1993
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Royal academy of medicine in Ireland section of biomedical sciences
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Irish cardiac society