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  1. Article

    Open Access

    Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer

    The majority of high-grade serous ovarian cancers (HGSCs) are deficient in homologous recombination (HR) DNA repair, most commonly due to mutations or hypermethylation of the BRCA1/2 genes. We aimed to discover h...

    I.-M. Launonen, N. Lyytikäinen, J. Casado, E. A. Anttila, A. Szabó… in Nature Communications (2022)

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  2. No Access

    Article

    The List of Possible Double and Multiple Open Clusters between Galactic Longitudes 240° and 270°

    Abstract—This work studies the candidate double and multiple open clusters (OCs) in the galactic sector from l = 240° to l = 270°, which contains the Vela-Puppis star formation region. To do that, we have searche...

    J. Casado in Astronomy Reports (2021)

  3. No Access

    Article

    Revisiting the mechanism of cementation: The role of hydrogen species in acidic aqueous media

    This paper presents the results of an analysis and summary of relevant literature on the mechanism of cementation of metals in acidic aqueous media, with the aim of reconsidering the conventional assumptions. ...

    J. Casado in Minerals & Metallurgical Processing (2018)

  4. Article

    Open Access

    The antigenic variability of HCV in viral HLA-Ag binding is related to the activation of the host immune response

    Our previous data show that hepatitis C virus (HCV) genotype 1 patients expressing the HLA-DQB1 * 0301 allele have a combined response probability of 69%, while the remaining 31% do not respond, probably becau...

    P. Muñoz de Rueda, S. M. Jiménez-Ruiz, R. Quiles… in Scientific Reports (2017)

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  5. No Access

    Article

    A methodology for the implementation of automated measuring stations in flexible manufacturing systems

    This paper presents a methodology for the inclusion of an automated measuring station in an existing flexible manufacturing system (FMS) by treating the measuring station as a workstation integrated into the F...

    A. Sanz, I. González, J. Casado… in The International Journal of Advanced Manu… (2013)

  6. No Access

    Article

    Spectroelectrochemical Raman Study of two α,α’-End Capped Sexithiophenes: The Effect of the Introduction of a Polarisable Sulfur Atom in the Side Chain

    In this paper, the vibrational FT-Raman spectra obtained at different anodic potentials chosen in the oxidation and reduction branches of the voltamperometric waves of two α,α’-sexithiophenes end capped with n-he...

    J. Casado, H. E. Katz, V. Hernández… in MRS Online Proceedings Library (2011)

  7. No Access

    Article

    Role of Antiretroviral Therapy in Long-Term Survival of Patients with AIDS-Related Pulmonary Aspergillosis

     The aim of the study presented here was to describe the clinical presentation and outcome of invasive pulmonary aspergillosis (IPA) in a cohort of HIV-infected patients and to assess factors associated with s...

    A. Moreno, M. Perez-Elías, J. Casado… in European Journal of Clinical Microbiology … (2000)

  8. No Access

    Article

    Nickel electrowinning using a Pt catalysed hydrogen-diffusion anode. Part I: Effect of chloride and sulfate ions and a magnetic field

    The use of a Pt catalysed H2-diffusion anode for Ni electrowinning has been studied from typical chloride, Watts and sulfate baths at 25 °C. Higher anodic current densities are found in a three-electrode cell whe...

    E. Brillas, J. Rambla, J. Casado in Journal of Applied Electrochemistry (1999)

  9. No Access

    Article

    Nickel electrowinning using a Pt catalysed hydrogen-diffusion anode. Part II: Batch tank with a sulphate bath

    A batch tank of 1.6L capacity has been designed for Ni electrowinning using a Pt catalysed H2-diffusion anode and a stainless steel/Ni cathode, both of 100cm2 area. The anode has high stability for sulphate baths...

    J. Rambla, E. Brillas, J. Casado in Journal of Applied Electrochemistry (1999)

  10. No Access

    Article

    Kinetics and mechanism of the ruthernium(III) catalyzed oxidation of propane-1,3-diol by alkaline hexacyanoferrate(III)

    The kinetics of oxidation of propane-1,3-diol by alkaline hexacyanoferrate (III) catalyzed by ruthenium trichloride has been studied spectrophotometrically. A reaction mechanism involving the formation of an i...

    A. E. Mucientes, F. J. Poblete, F. Santiago… in Reaction Kinetics and Catalysis Letters (1997)

  11. No Access

    Article

    Ab initio self-consistent reaction field calculations on amino acids: asparagine zwitterions in polar medium and gas phase

    A comparative theoretical study of the structure and vibrations of amino acid L-asparagine has been performed on the basis of ab initio Hartree-Fock calculations and the self-consistent reaction field theory. Th...

    J. T. López Navarrete, J. Casado, V. Hernández… in Theoretical Chemistry Accounts (1997)

  12. No Access

    Article

    Electrochemical extraction of oxygen from air via hydroperoxide ion

    A novel electrochemical method for the extraction of pure oxygen from air is described. The system consists of an undivided cell with a nickel anode, a carbon–polytetrafluoroethylene (CP) air-fed cathode and a...

    E. BRILLAS, A. MAESTRO, M. MORATALLA, J. CASADO in Journal of Applied Electrochemistry (1997)

  13. No Access

    Article

    Kinetics of the aminolysis and hydrolysis of alkyl nitrites: Evidence for an orbital controlled mechanism

    The kinetics of the nitrosation of piperidine by propyl,iso-propyl, butyl,iso-butyl,sec-butyl, andtert-butyl nitrites in 0.1M NaOH and of the hydrolysis of the nitrite esters were studied spectrophotometrically b...

    P. García-Santos, E. Calle… in Monatshefte für Chemie / Chemical Monthly (1996)

  14. No Access

    Chapter

    Vibrational Study of Amino Acid L-Asparagine in Aqueous Solution

    Amino acids, and asparagine in particular, have a zwitterionic structure in condensed phase. However, the structure of an isolated amino acid molecule can not be optimized by ab initio methods because the zwit...

    J. Casado, J. T. Lopez Navarrete, V. Hernandez… in Spectroscopy of Biological Molecules (1995)

  15. No Access

    Article

    Intestinal handling of a glucose gavage by the rat

    An oral gavage of either 3, 1 or 0.1 mmoles of 14C-labelled glucose was given to rats under standard feeding conditions or food deprived for 24 hr. The fate of the glucose label was determined at 10, 15, 30 and 6...

    J. A. Fernández-López, J. Casado, J. M. Argilés… in Molecular and Cellular Biochemistry (1992)

  16. No Access

    Article

    Role of the rat liver in the disposal of a glucose gavage

    An oral gavage of either 3, 1 or 0.1 mmoles of glucose was given to rats under standard feeding conditions or food deprived for 24 hr. The blood flow of the portal and suprahepatic veins as well as the hepatic...

    J. Casado, J. A. Fernández-López, M. J. Argilés… in Molecular and Cellular Biochemistry (1992)

  17. No Access

    Article

    Kinetic study of the oxidation of L-threonine by MnO 4 − ions

    A self-catalytic effect attributed to Mn2+ ions was observed when studying the oxidation of L-threonine by permanganate ions. The process obeys the rate equation:

    F. Andrés, A. Arrizabalaga, J. Casado, R. Peche in Reaction Kinetics and Catalysis Letters (1991)

  18. No Access

    Article

    Differences in L-alanine uptake by livers of Wistar and lean Zucker rats

    The L-alanine uptake by livers of Wistar and lean Zucker rats has been studied. The hepatic uptake and fractional extraction rates of alanine were estimated in 50–55 day old rats. No significant differences in...

    B. Ruiz, J. Casado, M. Pastor-Anglada, A. Felipe in Bioscience Reports (1991)

  19. No Access

    Article

    Kinetic study of the permanganate oxidation of DL-valine in acidic media

    The kinetics of permanganic oxidation of DL-valine in a concentrated sulfuric acid medium (3.0–5.0 M) has been studied by spectrophotometry. The rate law found shows that the reaction is autocatalyzed by Mn(II...

    A. Mucientes, F. J. Poblete, J. Casado in Reaction Kinetics and Catalysis Letters (1991)

  20. No Access

    Article

    Generalized Langevin equations with time-dependent temperature

    A generalized Langevin equation describing the evolution of a particle in a heat bath with a time-dependent temperature is derived for a simple model. The temperature is controlled by introducing dissipative t...

    J. J. Brey, J. Casado in Journal of Statistical Physics (1990)

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