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    Chapter

    Combining Microinjection with Microanalytical Methods to Investigate Regulation of Metabolic Pathways

    Microinjection is a powerful tool for studying the regulation of cellular function. It offers a distinct advantage over other techniques for investigating signal transduction pathways involved in acute hormona...

    J. Manchester, J. C. Lawrence Jr. in Microinjection (1999)

  2. Article

    Control of PHAS-I phosphorylation in 3T3-L1 adipocytes: effects of inhibiting protein phosphatases and the p70S6K signalling pathway

    PHAS-I is a recently discovered regulator of translation initiation. Non-phosphorylated PHAS-I binds and inhibits eukaryotic initiation factor-4E, the mRNA cap-binding protein that mediates a rate-limiting st...

    T.-A. Lin, J. C. Lawrence Jr. in Diabetologia (1997)

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