16 Result(s)

Article

Author Correction: Blood and adipose tissue steroid metabolomics and mRNA expression of steroidogenic enzymes in periparturient dairy cows differing in body condition

K. Schuh, S. Häussler, H. Sadri, C. Prehn, J. Lintelmann, J. Adamski… in Scientific Reports (2024)

Article

Blood and adipose tissue steroid metabolomics and mRNA expression of steroidogenic enzymes in periparturient dairy cows differing in body condition

In high-yielding dairy cows, the rapidly increasing milk production after parturition can result in a negative nutrient balance, since feed intake is insufficient to cover the needs for lactation. Mobilizing b...

K. Schuh, S. Häussler, H. Sadri, C. Prehn, J. Lintelmann, J. Adamski… in Scientific Reports (2022)

Article

The human metabolic profile reflects macro- and micronutrient intake distinctly according to fasting time

Although the impact of dietary patterns on human serum metabolites has been examined, the fasting effect on the metabolic profile has not yet been considered. The aim of this cross-sectional study is to invest...

A. Sedlmeier, A. Kluttig, I. Giegling, C. Prehn, J. Adamski… in Scientific Reports (2018)

Article

Instability of personal human metabotype is linked to all-cause mortality

Disruption of metabolic homeostasis is an important factor in many diseases. Various metabolites have been linked to higher risk of morbidity and all-cause mortality using metabolomics in large population-base...

M. E. Lacruz, A. Kluttig, D. Tiller, D. Medenwald, I. Giegling… in Scientific Reports (2018)

Article

Associations of anthropometric markers with serum metabolites using a targeted metabolomics approach: results of the EPIC-potsdam study

The metabolic consequences of type of body shape need further exploration. Whereas accumulation of body mass in the abdominal area is a well-established metabolic risk factor, accumulation in the gluteofemoral...

U Bachlechner, A Floegel, A Steffen, C Prehn, J Adamski, T Pischon… in Nutrition & Diabetes (2016)

Article

Linking diet, physical activity, cardiorespiratory fitness and obesity to serum metabolite networks: findings from a population-based study

It is not yet resolved how lifestyle factors and intermediate phenotypes interrelate with metabolic pathways. We aimed to investigate the associations between diet, physical activity, cardiorespiratory fitness...

A Floegel, A Wientzek, U Bachlechner, S Jacobs… in International Journal of Obesity (2014)

Article

Increased amino acids levels and the risk of develo** of hypertriglyceridemia in a 7-year follow-up

Recently, five branched-chain and aromatic amino acids were shown to be associated with the risk of develo** type 2 diabetes (T2D).

D. O. Mook-Kanamori, W. Römisch-Margl… in Journal of Endocrinological Investigation (2014)

Article

Alcohol-induced metabolomic differences in humans

Alcohol consumption is one of the world’s major risk factors for disease development. But underlying mechanisms by which moderate-to-heavy alcohol intake causes damage are poorly understood and biomarkers are ...

M Jaremek, Z Yu, M Mangino, K Mittelstrass, C Prehn, P Singmann… in Translational Psychiatry (2013)

Article

Schizophrenia shows a unique metabolomics signature in plasma

Schizophrenia is a severe complex mental disorder affecting 0.5–1% of the world population. To date, diagnosis of the disease is mainly based on personal and thus subjective interviews. The underlying molecula...

Y He, Z Yu, I Giegling, L **e, A M Hartmann, C Prehn, J Adamski… in Translational Psychiatry (2012)

Article

FLT3-regulated antigens as targets for leukemia-reactive cytotoxic T lymphocytes

The FMS-like tyrosine kinase 3 (FLT3) is highly expressed in acute myeloid leukemia (AML). Internal tandem duplications (ITD) of the juxtamembrane domain lead to the constitutive activation of the FLT3 kinase ...

B Brackertz, H Conrad, J Daniel, B Kast, H Krönig, D H Busch… in Blood Cancer Journal (2011)