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Article
Physiological and Transcriptome Analyses of Transgenic FGF21 Immature Rice Seeds
In addition to its role as one of the largest staple food crops in the world, rice (Oryza sativa L.) currently serves as an important bioreactor in molecular pharming. Although some studies have been conducted on...
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Article
Aberrant activation of liver X receptors impairs pancreatic beta cell function through upregulation of sterol regulatory element-binding protein 1c in mouse islets and rodent cell lines
Liver X receptors (LXR) are important transcriptional regulators of lipid and glucose metabolism. Our previous report demonstrated that LXR activation inhibited pancreatic beta cell proliferation through cell ...
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Article
Activation of liver X receptors inhibits pancreatic islet beta cell proliferation through cell cycle arrest
Liver X receptors (LXRs) are important transcriptional regulators of lipid homeostasis and proliferation in several cell types. However, the roles of LXRs in pancreatic beta cells have not been fully establish...
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Article
Prostaglandin E2 regulates Foxo activity via the Akt pathway: implications for pancreatic islet beta cell dysfunction
Prostaglandin E2 (PGE2) is a well-recognised inhibitor of glucose-stimulated insulin secretion (GSIS). The aim of this study was to investigate the signalling pathway of PGE2 in beta cell function regulation in H...
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Article
Relationship of total body fatness and five anthropometric indices in Chinese aged 20–40 years: different effects of age and gender
We aim to evaluate the ethnic-specific relationship of total fat mass and anthropometric indices in Chinese.