15 Result(s)

Article

Bilateral thermal capsulotomy with MR-guided focused ultrasound for patients with treatment-refractory obsessive-compulsive disorder: a proof-of-concept study

Despite optimal pharmacotherapy and cognitive-behavioral treatments, a proportion of patients with obsessive-compulsive disorder (OCD) remain refractory to treatment. Neurosurgical ablative or nondestructive s...

H H Jung, S J Kim, D Roh, J G Chang, W S Chang, E J Kweon, C-H Kim… in Molecular Psychiatry (2015)

Article

Induction of CD45 expression on bone marrow-derived mesenchymal stem cells

S-P Yeh, J-G Chang, W-J Lo, Y-C Liaw, C-L Lin, C-C Lee, C-F Chiu in Leukemia (2006)

Article

Mesenchymal stem cells can be easily isolated from bone marrow of patients with various haematological malignancies but the surface antigens expression may be changed after prolonged ex vivo culture

S-P Yeh, J-G Chang, C-L Lin, W-J Lo, C-C Lee, C-Y Lin, C-F Chiu in Leukemia (2005)

Article

Molecular basis of weak D in Taiwanese

Two genes, RHD and RHCE, encode the antigens of the RH blood group system. The weak D phenotype is caused by many different RHD alleles encoding aberrant RhD proteins, resulting in distinct serologic phenotype...

I.-L. Lin, M.-C. Shih, M.-H. Hsieh, T.-C. Liu, S.-E. Chang… in Annals of Hematology (2003)

Article

Association between apolipoprotein E genotype and outcome of traumatic brain injury

¶Background. The prognosis of traumatic brain injury is quite variable and not fully explained by the known factors. This study is to examine if the polymorphism of apolipoprotein E (apoE) influences the outcome ...

M.-F. Chiang, J.-G. Chang, C.-J. Hu in Acta Neurochirurgica (2003)

Article

Molecular characterization of deletional forms of β-thalassemia in Taiwan

β-Thalassemia is one of the most common genetic diseases in Taiwan. The most common mutations of β-globin are point mutations, and six mutations account for over 90% of cases. Less than 5% of the cases with β...

C.-T. Peng, S.-C. Liu, S.-S. Chiou, P.-L. Kuo, M.-C. Shih… in Annals of Hematology (2003)

Article

Lewis (FUT3) genotypes in Taiwanese, Thai, and Filipino populations

 The Lewis (Le) blood type comprises two major antigens, Le^a and Le^b, which are encoded by α (1,2)-fucosyltransferase (FUT2) and α (1,3/1,4)-fucosyltransferase (FUT3). In this study, we analyzed the mutations of ...

T. C. Liu, J. G. Chang, S. F. Lin, W. C. Chang, T. Y. Yang… in Annals of Hematology (2000)

Article

Molecular characterization of secretor type α(1,2)-fucosyltransferase gene deficiency in the Philippine population

 We analyzed the seven mutations which are responsible for the deficiency of the secretor type α(1,2)-fucosyltransferase gene product, Se enzyme, in the Philippine population. One hundred and one unrelated Fil...

C. T. Peng, C. H. Tsai, T. P. Lin, L. I. Perng, M. C. Kao… in Annals of Hematology (1999)

Article

Aberrant FHIT transcripts in hepatocellular carcinomas

To study abnormalities of the FHIT gene in human hepatocellular carcinoma (HCC), eight liver cancer cell lines, 18 matched tumorous and non-tumorous tissues from patients with HCC and three normal liver tissue...

Y-J Chen, P-H Chen, J-G Chang in British Journal of Cancer (1998)

Article

Molecular analysis of survival motor neuron (SMN) and neuronal apoptosis inhibitory protein (NAIP) genes of spinal muscular atrophy patients and their parents

We have assayed deletions of two candidate genes for spinal muscular atrophy (SMA), the survival motor neuron (SMN) and neuronal apoptosis inhibitory protein (NAIP) genes, in 101 patients from 86 Chinese SMA ...

J.-G. Chang, Yuh-Jyh Jong, Shuan-Pei Lin, Bing-Wen Soong, Chang-Hai Tsai… in Human Genetics (1997)

Article

Rapid detection of hemoglobin variants by mutagenically separate polymerase chain reaction (MS-PCR)

The detection of molecular defects of hemoglobin variants using mutagenically separated polymerase chain reaction (MS-PCR) was applied in this study. Using different lengths of allele-specific mutagenic primer...

J. G. Chang, C. P. Chang, C. M. Lu, J. M. Huang, J. T. Chen… in Annals of Hematology (1995)

Article

Rapid detection of −α ^4.2 deletion of α-thalassemia-2 by polymerase chain reaction

We sequenced part of the X boxes ofα-thalassemia-1 of Southeast Asia type (- -SEA) with−α ^4.2,−α ^3.7,−α ^G-Taichung, andα ^CSα. We found the X box of−α ^3.7 belonged to the X box of α2 globin gene and the X box ofα

J. G. Chang, T. C. Liu, S. S. Chiou, J. T. Chen, T. P. Chen… in Annals of Hematology (1994)

Article

Rapid molecular characterization of Hb H disease in Chinese by polymerase chain reaction

We have developed a rapid method to molecularly distinguish different types of Hb H disease. The study depended on (a) most of the Hb H disease in Taiwan having anα-thalassemia-1 of the Southeast Asia type (-SEA)...

J. G. Chang, T. C. Liu, L. I. Perng, S. S. Chiou, T. P. Chen… in Annals of Hematology (1994)