Page
%P
-
Article
Open AccessAssociation between cyclo-oxygenase-2 overexpression and missense p53 mutations in gastric cancer
Wild-type p53 competitively binds to the promoter region of COX-2 in vitro and inhibits its transcription. We examined the association between p53 mutation and COX-2 expression in gastric cancer. COX-2 over-expre...