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Article
Open AccessDetermination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children
The Fat mass and obesity-associated gene (FTO) was the first gene reliably associated with body mass index in genome-wide association studies on a population level. At present, the genetic variations within the F...
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Article
Novel genetic variant in FTO influences insulin levels and insulin resistance in severely obese children and adolescents
The global prevalence of obesity and overweight is increasing rapidly among adults as well as among children and adolescents. Recent genome-wide association studies have provided strong support for association...