8 Result(s)
within
Biomedicine
Epidemiology
J Kim
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Article
Prospective multicenter cohort study of estrogen and insulin-like growth factor system in BRCA mutation carriers
Major clinical characteristics of BRCA1/2-related cancers include association with estrogen and metabolic consequences. We aimed to evaluate serum estradiol (E2) and insulin-like growth factor 1 (IGF-1) levels as...
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Article
Open AccessEvaluation of survival benefits by platinums and taxanes for an unfavourable subset of carcinoma of unknown primary: a systematic review and meta-analysis
Although chemotherapeutic regimens containing a taxane or platinum agent have been widely recommended for unfavourable carcinoma of unknown primary (CUP), no evidence exists for the superiority of any administ...
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Article
Open AccessHuman papillomavirus predicts outcome in oropharyngeal cancer in patients treated primarily with surgery or radiation therapy
This study examines the prognostic significance of human papillomavirus (HPV) in patients with locally advanced oropharyngeal squamous cell carcinoma (SCC) treated primarily with surgery or definitive radiothe...
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Article
Open AccessEWS-Oct-4B, an alternative EWS-Oct-4 fusion gene, is a potent oncogene linked to human epithelial tumours
Characterisation of EWS-Oct-4 translocation fusion product in bone and soft-tissue tumours revealed a chimeric gene resulting from an in-frame fusion between EWS (Ewing's sarcoma gene) exons 1–6 and Oct-4 exons 1...
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Article
Open AccessMutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients
Somatic mutations of LKB1 tumour suppressor gene have been detected in human cancers including non-small cell lung cancer (NSCLC). The relationship between LKB1 mutations and clinicopathological characteristics a...
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Article
Open AccessVaccination of metastatic renal cell carcinoma patients with autologous tumour-derived vitespen vaccine: clinical findings
The aim of this study was to evaluate the clinical efficacy as determined by time to progression and response rate (RR) of autologous vitespen (formerly HSPPC-96; Oncophage, Antigenics Inc., New York, NY, USA)...
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Article
Open AccessA single institutional experience of thymic epithelial tumours over 11 years: clinical features and outcome and implications for future management
Thymic epithelial tumours (TETs), the most common tumour of the anterior mediastinum, are epithelial neoplasms of the thymus with a wide spectrum of morphologic features. We retrospectively analysed clinical f...
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Article
Open AccessAlternating dose-dense chemotherapy in patients with high volume disseminated non-seminomatous germ cell tumours
Only about half of patients with a poor-prognosis non-seminomatous germ-cell tumours can achieve a cure. The aim of this phase II study was to assess the efficacy and toxicity of a dose-dense alternating chemo...
