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Article
Impact of malignancy on Clostridium difficile infection
The purpose of this study was to investigate the impact of malignancy and chemotherapy on the clinical and microbiological characteristics of Clostridium difficile infections (CDI).
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Article
Open AccessSignificance of KIT exon 17 mutation depends on mutant level rather than positivity in core-binding factor acute myeloid leukemia
KIT exon 17 mutation is a poor prognostic factor in core-binding factor acute myeloid leukemia. However, the mutation detection method used for risk assessment is not assigned. It is necessary to verify the analy...
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Article
Prospective multicenter cohort study of estrogen and insulin-like growth factor system in BRCA mutation carriers
Major clinical characteristics of BRCA1/2-related cancers include association with estrogen and metabolic consequences. We aimed to evaluate serum estradiol (E2) and insulin-like growth factor 1 (IGF-1) levels as...
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A Pilot Study of BRCA Mutation Carriers’ Knowledge About the Clinical Impact of Prophylactic-oophorectomy and Views on Fertility Consultation: A Single-Center Pilot Study
BRCA mutation carriers will experience early surgically induced menopause following prophylactic bilateral sal**o-oophorectomy (PBSO). This pilot study aimed to investigate their (1) knowledge about the clinica...
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Article
Efficient lung orthotopic tumor-growth suppression of oncolytic adenovirus complexed with RGD-targeted bioreducible polymer
Oncolytic adenoviruses (Ad) have been developed for the eradication of tumors. Although they hold much promise as a cancer therapy, they have a short blood circulation time and high liver toxicity. An effectiv...
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Article
Impact of a computerized alert system for bacteremia notification on the appropriate antibiotic treatment of Staphylococcus aureus bloodstream infections
A computerized alert system (CAS) has been introduced to notify bacteremia in real time. We evaluated the impact of the CAS on the administration of appropriate antibiotics in patients with Staphylococcus aureus ...
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Open AccessO069: Efficacy of cleaning methods post-inoculation of pathogenic microorganisms of conventional and novel cleankeys computer keyboards
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Open AccessEvaluation of survival benefits by platinums and taxanes for an unfavourable subset of carcinoma of unknown primary: a systematic review and meta-analysis
Although chemotherapeutic regimens containing a taxane or platinum agent have been widely recommended for unfavourable carcinoma of unknown primary (CUP), no evidence exists for the superiority of any administ...
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Article
A review of RGD-functionalized nonviral gene delivery vectors for cancer therapy
The development of effective treatments that enable many patients suffering from cancer to be successfully cured is highly demanded. Angiogenesis, which is a process for the formation of new capillary blood ve...
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Article
Open AccessAntibodies to the envelope protein protect macaques from SIVmac251 acquisition in an immunization regimen that mimics the RV-144 Thai trial
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Open AccessEarly immune events during acute HIV infection
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Article
Open AccessDistinct gene expression profiles associated with the susceptibility of pathogen-specific CD4+ T cells to HIV-1 infection
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Open AccessIncident cases characterization and deep sequencing provide new insight into multiplicity of infection and HIV evolution in very early acute infection
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Article
Open AccessVector induced skewing of antibody Fc-effector functions
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Open AccessVaccine-induced ADCC-mediating antibodies target unique and overlap** envelope epitopes
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Article
Open AccessDesign of an HIV Env antigen that binds with high affinity to antibodies against linear, conformational and broadly neutralizing epitopes within V1/V2
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Article
Pretreatment with erythropoietin attenuates the neurological injury after spinal cord ischemia
Experimental study.
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Article
The measurement of backscatter factors of kilovoltage X-ray beams using Gafchromic™ EBT2 film
Backscatter factors are essential in the determination of radiation dose for kilovoltage X-ray beams. The accurate measurement of backscatter factors in water (B W) is difficult and publis...
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Article
Open AccessHuman papillomavirus predicts outcome in oropharyngeal cancer in patients treated primarily with surgery or radiation therapy
This study examines the prognostic significance of human papillomavirus (HPV) in patients with locally advanced oropharyngeal squamous cell carcinoma (SCC) treated primarily with surgery or definitive radiothe...
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Article
Open AccessEWS-Oct-4B, an alternative EWS-Oct-4 fusion gene, is a potent oncogene linked to human epithelial tumours
Characterisation of EWS-Oct-4 translocation fusion product in bone and soft-tissue tumours revealed a chimeric gene resulting from an in-frame fusion between EWS (Ewing's sarcoma gene) exons 1–6 and Oct-4 exons 1...
