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  1. Article

    Open Access

    Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis

    Although evidence for mitochondrial dysfunction in the pathogenesis of bipolar disorder (BD) has been reported, the precise biological basis remains unknown, hampering the search for novel biomarkers. In this ...

    N Yoshimi, T Futamura, S E Bergen, Y Iwayama, T Ishima, C Sellgren… in Molecular Psychiatry (2016)

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  2. No Access

    Article

    Knee arthroscopy routines and practice

    Knee arthroscopy is one of most commonly performed day-case orthopaedic procedures, thus consuming huge medical resources. The aim of the present questionnaire survey was to study knee arthroscopy routines and...

    M. Brattwall, E. Jacobson, M. Forssblad… in Knee Surgery, Sports Traumatology, Arthros… (2010)

  3. No Access

    Article

    A novel polymorphism in the 17β-hydroxysteroid dehydrogenase type 5 (aldo-keto reductase 1C3) gene is associated with lower serum testosterone levels in caucasian men

    Genetic variation in the androgen metabolizing enzymes is important to identify and feature as they may influence the risk of prostate cancer and help clarify the etiology of the disease. Human 17β-hydroxysteroid...

    J Jakobsson, E Palonek, M Lorentzon, C Ohlsson, A Rane… in The Pharmacogenomics Journal (2007)

  4. No Access

    Article

    Efficient transduction of neurons using Ross River glycoprotein-pseudotyped lentiviral vectors

    Lentiviral vectors are promising tools for CNS gene transfer since they efficiently transduce the cells of the nervous system in vivo. In this study, we have investigated the transduction efficiency of lentiviral...

    J Jakobsson, T Tolstrup Nielsen, K Staflin, B Georgievska, C Lundberg in Gene Therapy (2006)

  5. No Access

    Article

    A functional C–G polymorphism in the CYP7B1 promoter region and its different distribution in Orientals and Caucasians

    Cytochrome P450 (CYP) 7B1 is involved in many metabolic processes including androgen metabolism. Genetic variation in the CYP7B1 gene may play a role in predisposition to prostate cancer. Here, we screened the hu...

    J Jakobsson, H Karypidis, J-E Johansson, H-K Roh, A Rane… in The Pharmacogenomics Journal (2004)

  6. Article

    Measurement of extravascular lung water by thermal-dye dilution technique: mechanisms of cardiac output dependence

    The extent to which extravascular lung water (EVLW) is dependent on cardiac output was analysed in anaesthetized and mechanically ventilated pigs. EVLW was measured by thermal-dye dilution technique, by a fibr...

    C. -J. Wickerts, J. Jakobsson, C. Frostell, G. Hedenstierna MD in Intensive Care Medicine (1990)

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  7. Article

    Measurement of extravascular lung water by thermal-dye dilution technique: Mechanisms of cardiac output dependence

    The extent to which extravascular lung water (EVLW) is dependent on cardiac output was analysed in anaesthetized and mechanically ventilated pigs. EVLW was measured by thermal-dye dilution technique, by a fibr...

    C. -J. Wickerts, J. Jakobsson, C. Frostell, G. Hedenstierna MD in Intensive Care Medicine (1990)

    Download PDF (630 KB)