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  1. Article

    Open Access

    Biodegradable interstitial release polymer loading a novel small molecule targeting Axl receptor tyrosine kinase and reducing brain tumour migration and invasion

    Glioblastoma multiforme (GBM) is the most common and aggressive brain tumour. The neoplasms are difficult to resect entirely because of their highly infiltration property and leading to the tumour edge is uncl...

    S-Y Yen, S-R Chen, J Hsieh, Y-S Li, S-E Chuang, H-M Chuang, M-H Huang, S-Z Lin… in Oncogene (2016)

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  2. No Access

    Article

    Melanopsin signalling in mammalian iris and retina

    Non-mammalian vertebrates have an intrinsically photosensitive iris and thus a local pupillary light reflex (PLR). In contrast, it is thought that the PLR in mammals generally requires neuronal circuitry conne...

    T. Xue, M. T. H. Do, A. Riccio, Z. Jiang, J. Hsieh, H. C. Wang, S. L. Merbs… in Nature (2011)

  3. Article

    The glucagon-like peptide 1 receptor is essential for postprandial lipoprotein synthesis and secretion in hamsters and mice

    Glucagon-like peptide 1 (GLP-1) receptor (GLP-1R) agonists and dipeptidyl peptidase-4 (DPP-4) inhibitors attenuate postprandial lipaemia through mechanisms that remain unclear. As dyslipidaemia is a contributi...

    J. Hsieh, C. Longuet, C. L. Baker, B. Qin, L. M. Federico, D. J. Drucker… in Diabetologia (2010)

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  4. No Access

    Article

    Realization and characterization of SU-8 micro cylindrical lenses for in-plane micro optical systems

    This study presents a new method of fabricating and integrating micro cylindrical lenses (MCLs) into an in-plane micro optical system. The characterizations of MCLs, which are made of SU-8 negative photoresist...

    J. Hsieh, C.-J. Weng, H.-L. Yin, H.-H. Lin, H.-Y. Chou in Microsystem Technologies (2005)

  5. No Access

    Chapter and Conference Paper

    Some Limit Theorems on Simulated Annealing

    Many combinatorial optimization problems can be described as finding the global minimum of a certain function U(•) over a finite state space S, say, {l, 2,…, N}. A commonly used approach is the gradient method...

    T. S. Chiang, Y. Chow, J. Hsieh in Stochastic Models, Statistical Methods, an… (1992)

  6. No Access

    Chapter

    Mixing Processes in the Flocculation of Microcrystalline Cellulose Sols with Cationic Polymers

    In order to meet the many diverse end uses of paper, a large variety of chemicals is added to pulp fibers. As most of these chemicals are added at the wet end of a paper machine, relatively small amounts are m...

    Philip Luner, J. Hsieh, R. Evans in Polymer Colloids II (1980)

  7. No Access

    Article

    Simulation des Einflusses von Translations- und Schwingungsenergie auf die Reaktionen von H- und DAtomen mit HCI und DCI

    T. Valencich, J. Hsieh, J. Kwan, T. Stewart, T. Lenhardt in Colloid and Polymer Science (1978)