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Chapter
Mechanism Underlying Physiological Modulation of Myocardial Contraction by Taurine
One of the established actions of taurine is the modulation of myocardial contraction. Initial studies demonstrating this effect employed pharmacological doses of taurine to alter contractile function1–3. Althoug...
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Chapter
Antiarrhythmic Action of Taurine
Taurine (2-aminoethane sulfonic acid), a ß-amino acid present in human diet, is one of the most abundant sulfur containing amino acids in mammalian tissues, found in excess of 30 µmol/g tissue in rat heart1,2. Ta...
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Article
Oil and fat hydrolysis with lipase fromAspergillus sp.
Hydrolysis of olive oil, soybean oil, mink fat, lard, palm oil, coconut oil, and a hydrogenated, hardened oil with lipase from anAspergillus sp. has been studied. The lipase had high specific activity (60,000 U/g...
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Article
Control of Sizes and Optical Emission of Sige Quantum Dots Prepared on Ordered Mesoporous Silica Coated Si Wafer
A new way of preparing wafer sized SiGe and Ge quantum dots at extremely low cost is presented. The results show that two different controlled nanometer sizes of the quantum dots can be formed simultaneously i...
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Article
Infinite-Dimensional Linear Dynamical Systems with Chaoticity
The authors present two results on infinite-dimensional linear dynamical systems with chaoticity. One is about the chaoticity of the backward shift map in the space of infinite sequences on a general Fréchet ...
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Article
Polymorphisms in the 5′-untranslated region of the human serotonin receptor 1B (HTR1B) gene affect gene expression
We present evidence of complex balancing regulation of HTR1B transcription by common polymorphisms in its promoter. Computational analysis of the HTR1B gene predicted that a 5′ segment, spanning common DNA sequen...
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Article
Multicenter linkage study of schizophrenia loci on chromosome 22q
The hypothesis of the existence of one or more schizophrenia susceptibility loci on chromosome 22q is supported by reports of genetic linkage and association, meta-analyses of linkage, and the observation of e...
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Article
Haplotypic association spanning the 22q11.21 genes COMT and ARVCF with schizophrenia
Catechol-O-methyltransferase (COMT) has been implicated in schizophrenia by its function through its roles in monoamine neurotransmitter metabolism and its impact on prefrontal cognition, and also by its position...
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Chapter and Conference Paper
A Kind of Channel-Section Beam Element for Transient Coupled Thermal-Structural Dynamic Analysis
Thermally induced vibrations of spacecraft appendages with frame- and truss-type structures have been a recurrent problem for over 40 years. When an appendage is subjected to sudden heating exchanges, the defo...
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Article
Ergodic dynamics of the coupled quasigeostrophic-flow-energy-balance system
The authors consider a mathematical model for the coupled atmosphere-ocean system, namely, the coupled quasigeostrophic-flow-energy-balance model. This model consists of the large-scale quasigeostrophic oceani...
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Article
Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2
We and others have previously reported linkage to schizophrenia on chromosome 10q25–q26 but, to date, a susceptibility gene in the region has not been identified. We examined data from 3606 single-nucleotide p...
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Article
Open AccessFast and accurate method for flexible ligand superposition and shapebased screening
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Article
Meta-analysis of 32 genome-wide linkage studies of schizophrenia
A genome scan meta-a nalysis (GSMA) was carried out on 32 independent genome-wide linkage scan analyses that included 3255 pedigrees with 7413 genotyped cases affected with schizophrenia (SCZ) or related disor...
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Article
Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms
A genomewide linkage scan was carried out in eight clinical samples of informative schizophrenia families. After all quality control checks, the analysis of 707 European-ancestry families included 1615 affecte...
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Article
Open AccessAnalysis and comparison of 2D fingerprints: insights into database screening performance using eight fingerprint methods
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Article
GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia
We conducted data-mining analyses using the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) and molecular genetics of schizophrenia genome-wide association study supported by the genetic as...
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Article
Open AccessNatural Killer (NK) cell responses at female genital mucosa to SIV vaginal challenge
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Article
Open AccessPTEN-regulated AKT/FoxO3a/Bim signaling contributes to reactive oxygen species-mediated apoptosis in selenite-treated colorectal cancer cells
Mounting evidence shows that selenium possesses chemotherapeutic potential against tumor cells, including leukemia, prostate cancer and colorectal cancer (CRC) cells. However, the detailed mechanism by which s...
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Article
Process Modeling of Low-Pressure Die Casting of Aluminum Alloy Automotive Wheels
Although on initial inspection, the aluminum alloy automotive wheel seems to be a relatively simple component to cast based on its shape, further insight reveals that this is not the case. Automotive wheels ar...
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Article
mTORC1 enhancement of STIM1-mediated store-operated Ca2+ entry constrains tuberous sclerosis complex-related tumor development
The protein complex of tuberous sclerosis complex (TSC)1 and TSC2 tumor suppressors is a key negative regulator of mammalian target of rapamycin (mTOR). Hyperactive mTOR signaling due to the loss-of-function o...
