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Article
GATA3 targets semaphorin 3B in mammary epithelial cells to suppress breast cancer progression and metastasis
Semaphorin 3B (SEMA3B) is a secreted axonal guidance molecule that is expressed during development and throughout adulthood. Recently, SEMA3B has emerged as a tumor suppressor in non-neuronal cells. Here, we show...
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Article
Immune escape from NY-ESO-1-specific T-cell therapy via loss of heterozygosity in the MHC
Adoptive immunotherapy of tumors with T cells specific for the cancer-testis antigen NY-ESO-1 has shown great promise in preclinical models and in early stage clinical trials. Tumor persistence or recurrence a...
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Article
PARP1 and DNA-PKcs synergize to suppress p53 mutation and telomere fusions during T-lineage lymphomagenesis
Poly(ADP-ribose) polymerase 1 (PARP1) interacts genetically with the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) to suppress early-onset T-lineage lymphomas in the mouse, but the underlying mecha...
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Chapter and Conference Paper
Nigrostriatal alterations in bone morphogenetic protein receptor II dominant negative mice
We previously demonstrated that exogenous application of bone morphogenetic protein 7 (BMP7) reduced 6-hydroxydopamine-mediated neurodegeneration in a rodent model of Parkinson’s disease. The purpose of this s...
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Article
Amplified wavelength–time transformation for real-time spectroscopy
Real-time spectroscopy provides invaluable information about the evolution of dynamical processes, especially non-repetitive phenomena. Unfortunately, the continuous acquisition of rapidly varying spectra repr...
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Article
Four-dimensional data assimilation method based on SVD: Theoretical aspect
A new method of four-dimensional data assimilation based on Singular Value Decomposition (SVD) is proposed. In it, a set of atmospheric states is obtained by integrating a numerical weather prediction model an...
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Article
On the Computational Complexity of Consumer Decision Rules
A consumer entering a new bookstore can face more than 250,000alternatives. The efficiency of compensatory and noncompensatory decisionrulesfor finding a preferred item depends on the efficiency of their assoc...
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Article
Two-Stage Budgeting: A Difficult Problem
Utility maximization with a weakly separable utility function requires aconsumer create an optimal budget for each separable subgroup. We show thatcomputational complexity of optimal budgeting is the maximum o...
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Article
Introductory honors economics on the Web
Economics 304KH and 304LH at The University of Texas at Austin are introductory honors economics courses. Our goal was to provide students with more advanced material than available in introductory textbooks, ...
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Article
Eine neue Möglichkeit zur Verhinderung der Ototoxicität des Streptomycins