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Open AccessGuaiac faecal occult blood test performance at initial and repeat screens in the English Bowel Cancer Screening Programme
In many countries, screening for colorectal cancer (CRC) relies on repeat testing using the guaiac faecal occult blood test (gFOBT). This study aimed to compare gFOBT performance measures between initial and r...
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Article
Modelling the Economics of Type 2 Diabetes Mellitus Prevention: A Literature Review of Methods
Our objective was to review modelling methods for type 2 diabetes mellitus prevention cost-effectiveness studies. The review was conducted to inform the design of a policy analysis model capable of assisting r...
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Open AccessReply: cost-effectiveness of population-based screening for colorectal cancer
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Cost of care for colorectal cancer in Ireland: a health care payer perspective
Management options for colorectal cancer have expanded in recent years. We estimated average lifetime cost of care for colorectal cancer in Ireland in 2008, from the health care payer perspective.
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Open AccessCost-effectiveness of population-based screening for colorectal cancer: a comparison of guaiac-based faecal occult blood testing, faecal immunochemical testing and flexible sigmoidoscopy
Several colorectal cancer-screening tests are available, but it is uncertain which provides the best balance of risks and benefits within a screening programme. We evaluated cost-effectiveness of a population-...
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The costs and benefits of bowel cancer service developments using discrete event simulation
Colorectal cancer includes cancerous growths in the colon, rectum and appendix and affects around 30 000 people in England each year. Maximizing health benefits for patients with colorectal cancer requires con...
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Assessment of a 7-day turn-around for the reporting of cervical smear results using discrete event simulation
A discrete event simulation (DES) model has been used to analyse options with the potential to facilitate a 7-day turn-around of cervical screening results in England, with the aim of reducing the anxiety expe...
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Open AccessCost-effectiveness of oxaliplatin and capecitabine in the adjuvant treatment of stage III colon cancer
For many years, the standard treatment for stage III colon cancer has been surgical resection followed by 5-fluorouracil in combination with folinic acid (5-FU/LV). Ongoing clinical trial evidence suggests tha...
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Commentary on Coyle et al., "The assessment of the economic return from controlled clinical trials"