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  1. Article

    Open Access

    Oral administration of porcine epidemic diarrhea virus spike protein expressing in silkworm pupae failed to elicit immune responses in pigs

    The silkworm (Bombyx mori) and its pupae have been used for decades as nutritional additives and applied on the production of high-quality recombinant proteins via the baculovirus expression vector (BEV) system. ...

    Chia-Yu Chang, Wei-Ting Hsu, Pei-Shiue Tsai, Chi-Min Chen, Ivan-Chen Cheng… in AMB Express (2020)

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  2. Article

    Open Access

    Identification of Neutralizing Monoclonal Antibodies Targeting Novel Conformational Epitopes of the Porcine Epidemic Diarrhoea Virus Spike Protein

    Since 2010, newly identified variants of porcine epidemic diarrhoea virus (PEDV) have caused high mortality in neonatal piglets which has devastated the swine industry. The spike (S) glycoprotein of PEDV conta...

    Chia-Yu Chang, Ivan-Chen Cheng, Yen-Chen Chang, Pei-Shiue Tsai… in Scientific Reports (2019)

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  3. Article

    Open Access

    Peptides mimicking viral proteins of porcine circovirus type 2 were profiled by the spectrum of mouse anti-PCV2 antibodies

    Porcine circovirus 2 (PCV2) is a small, non-enveloped DNA virus causing swine lymphocyte depletion and severe impact on the swine industry. The aim of this study was to evaluate the antigenicity and immunogeni...

    Ling-Chu Hung, Cheng-Yao Yang, Ivan-Chen Cheng in BMC Immunology (2017)

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