Skip to main content

3 Result(s)

within Ivan Ulč Remove this filter

and

  1. Article

    Open Access

    Pharmacodynamic and pharmacokinetic behavior of landiolol during dobutamine challenge in healthy adults

    To study the pharmacokinetic and -dynamic behavior of landiolol in the presence of dobutamine in healthy subjects of European ancestry.

    Günther Krumpl, Ivan Ulč, Michaela Trebs… in BMC Pharmacology and Toxicology (2020)

    Download PDF (1024 KB) View Article

  2. No Access

    Article

    Single-Dose Pharmacokinetics and Tolerability of Aprocitentan, a Dual Endothelin Receptor Antagonist, in Subjects with Severe Renal Function Impairment

    The orally active dual endothelin receptor antagonist aprocitentan targets a novel pathway in the treatment of hypertension and could be a key player in the treatment of salt/volume-dependent hypertension. Its...

    Patricia N. Sidharta, Ivan Ulč, Jasper Dingemanse in Clinical Drug Investigation (2019)

  3. No Access

    Article

    Biocomparison Study of Adult and Paediatric Dose Strengths of the Prostacyclin Receptor Agonist Selexipag

    Selexipag is an oral, non-prostanoid, selective prostacyclin receptor agonist recently marketed for the treatment of pulmonary arterial hypertension (PAH) in adults. Selexipag may also be an effective treatmen...

    Margaux Boehler, Shirin Bruderer, Ivan Ulč… in European Journal of Drug Metabolism and Ph… (2018)