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Open AccessConcerns on modeling postmenopausal osteoporosis on young female rats
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Serum 25-hydroxyvitamin D status, quantitative ultrasound parameters, and their determinants in Greek population
Vitamin D deficiency and quantitative ultrasound measurements are associated with bone fragility. We assessed these parameters and their correlates. 87.7% of the population has vitamin D inadequacy and this co...
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Changes of serum sclerostin and Dickkopf-1 levels during the menstrual cycle. A pilot study
Studies in postmenopausal women have identified sclerostin as a strong candidate for mediating estrogen effects on the skeleton. The effects of estradiol on sclerostin and Dickkopf-1 in younger women remain un...
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Assessment of body composition in Wistar rat offspring by DXA in relation to prenatal and postnatal nutritional manipulation
This experimental study aims to investigate the impact of combinations of prenatal and postnatal food manipulation on body composition in rat offspring.
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Useful animal models for the research of osteoarthritis
Osteoarthritis (OA) is a major cause of suffering for millions of people. Investigating the disease directly on humans may be challenging. The aim of the present study is to investigate the advantages and limi...
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Metabolic profiles of adult Wistar rats in relation to prenatal and postnatal nutritional manipulation: The role of birthweight
This experimental study aimed to prospectively investigate the impact of combinations of prenatal and postnatal food manipulations on the metabolic profile of adult offspring.
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Effect of parathyroidectomy versus risedronate on volumetric bone mineral density and bone geometry at the tibia in postmenopausal women with primary hyperparathyroidism
The objective of the study was to evaluate the effect of parathyroidectomy (PTX) versus 35 mg once-weekly (ow) risedronate administration on volumetric bone mineral density (vBMD) and bone geometry at the tibi...
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Hepatic Injury Due to Combined Choline-Deprivation and Thioacetamide Administration: An Experimental Approach to Liver Diseases
The induction of prolonged choline-deprivation (CD) in rats receiving thioacetamide (TAA) is an experimental approach of mild hepatotoxicity that could resemble commonly presented cases in clinical practice (i...
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Choline-deprivation alters crucial brain enzyme activities in a rat model of diabetic encephalopathy
Diabetic encephalopathy describes the moderate cognitive deficits, neurophysiological and structural central nervous system changes associated with untreated diabetes. It involves neurotoxic effects such as th...
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Impact of Nesiritide on Renal Function and Mortality in Patients Suffering from Heart Failure
Acutely decompensated congestive heart failure is a major public health problem, with constantly rising prevalence, morbidity, mortality and need for hospitalization in both America and Europe. In 2001, the FD...