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Article
Open AccessImpact of dose reductions on adjuvant abemaciclib efficacy for patients with high-risk early breast cancer: analyses from the monarchE study
In monarchE, adjuvant abemaciclib significantly improved invasive disease-free survival (IDFS) and distant relapse-free survival (DRFS), with sustained benefit beyond the 2-year treatment period. Abemaciclib d...
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Article
Is there any prognostic significance in pleural involvement and/or effusion in patients with ALK-positive NSCLC?
Anaplastic lymphoma kinase (ALK) mutations occurs in approximately 3–5% of patients with non-small cell lung cancer (NSCLC). Pleural involvement/effusion is common in ALK-positive patients with NSCLC at baseli...
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Article
Open AccessCorrection: Efficacy of subsequent treatments in patients with hormone-positive advanced breast cancer who had disease progression under CDK 4/6 inhibitor therapy
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Article
Open AccessEfficacy of subsequent treatments in patients with hormone-positive advanced breast cancer who had disease progression under CDK 4/6 inhibitor therapy
There is no standard treatment recommended at category 1 level in international guidelines for subsequent therapy after cyclin-dependent kinase 4/6 inhibitor (CDK4/6) based therapy. We aimed to evaluate which ...
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Article
Open AccessEfficacy and safety of trifluridine/tipiracil in older and younger patients with metastatic gastric or gastroesophageal junction cancer: subgroup analysis of a randomized phase 3 study (TAGS)
Trifluridine and tipiracil (FTD/TPI) demonstrated survival benefit vs placebo and manageable safety in previously treated patients with metastatic gastric/gastroesophageal junction cancer (mGC/GEJC) in the ran...
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Article
Prognostic Factors for Survival in Transverse Colon Cancers
Transverse colon cancer (TCC) is a rare condition that accounts for 10% of all colon cancers. TCC was accepted more likely right-sided colon cancers. We aimed to investigate whether TCC differs from other colo...
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Article
Prognostic nutritional index and its dynamics after curative treatment are independent prognostic factors on survival in non-metastatic nasopharyngeal carcinoma
We aimed to identify the prognostic and predictive values of post-treatment prognostic nutritional index (PNI) and PNI dynamics in nasopharyngeal cancer patients (NPC) in this study.
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Article
Open AccessEfficacy and safety of cabozantinib for patients with advanced hepatocellular carcinoma based on albumin-bilirubin grade
Albumin-bilirubin (ALBI) grade is an objective measure of liver function for patients with hepatocellular carcinoma (HCC). The tyrosine kinase inhibitor cabozantinib is approved for patients with advanced HCC ...
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Article
Investigation of the relationship between GSTM1 gene variations and serum trace elements, plasma malondialdehyde levels in patients with colorectal cancer
The aim of this study is to investigate of the relationship between GSTM1 gene variations and serum trace elements, plasma malondialdehyde levels in patient with colorectal cancer.
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Article
Open AccessEconomic burden of lung cancer in Turkey: a cost of illness study from payer perspective
This study was designed to estimate economic burden of lung cancer in Turkey from payer perspective based on expert panel opinion on practice patterns in clinical practice.
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Article
Contrast nephropathy in cancer patients receiving anti-VEGF therapy: a prospective study
Contrast nephropathy risk has been increasing in cancer patients. Nephrotoxic side effects of anti-vascular endothelial growth factor/receptor (anti-VEGF/R) drugs used in oncologic treatment are also prominent...
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Article
Prognostic factors and oncological outcomes of ovarian yolk sac tumors: a retrospective multicentric analysis of 99 cases
To investigate the clinico-pathological prognostic factors and treatment outcomes in patients with ovarian yolk sac tumors (YST).
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Article
Changes in skeletal muscle area and lean body mass during pazopanib vs sunitinib therapy for metastatic renal cancer
To evaluate whether sunitinib and pazopanib treatments are associated with change in skeletal muscle area (SMA) and total lean body mass (LBM) as well as to compare their efficacies and safety profiles in pati...
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Pregnancy and Gastrointestinal Cancers
The second most common cause of death for women in reproductive age is cancer. The mean age of mothers is on the rise today. As the incidence of cancer rises with age, the incidence of cancer during pregnancy ...
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Chapter
Bone-Targeted Therapy in Advanced Breast Cancer
The bone is one of the three most common metastatic sites of breast cancer. Bone metastatic disease has a favorable prognosis compared to visceral metastatic disease, but skeletal event (pain, pathologic fract...
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Article
Regorafenib or rechallenge chemotherapy: which is more effective in the third-line treatment of metastatic colorectal cancer?
To assess the efficacy and safety of regorafenib versus rechallenge chemotherapy in previously treated mCRC patients in third-line setting.
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Chapter
Bone-Targeted Therapy in Early Breast Cancer
Early-stage breast cancer has a favorable prognosis, so long-term survivorship is important. Systemic adjuvant therapy may result in chronic adverse events, including osteoporosis. Accelerated bone loss may oc...
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Chapter
Bone-Directed Therapy and Breast Cancer: Bisphosphonates, Monoclonal Antibodies, and Radionuclides
Breast cancer bone metastasis causes severe morbidity and is commonly encountered in daily clinical practice. It causes pain, pathologic fractures, spinal cord, and other nerve compression syndromes and life-t...
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Article
Erratum to: Single-agent bevacizumab is an effective treatment in recurrent glioblastoma
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Article
Single-agent bevacizumab is an effective treatment in recurrent glioblastoma
The aim of this study was to evaluate the efficiency and safety of single-agent bevacizumab therapy for recurrent glioblastoma multiforme (GBM). We identified patients with histologically confirmed glioblasto...
