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Article
Open AccessSerotonin modulates excitatory synapse maturation in the develo** prefrontal cortex
Serotonin (5-HT) imbalances in the develo** prefrontal cortex (PFC) are linked to long-term behavioral deficits. However, the synaptic mechanisms underlying 5-HT-mediated PFC development are unknown. We foun...
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Article
N-type Cav channel inhibition by spider venom peptide of Argiope bruennichi
The spider venom is composed of various bioactive peptides and has well-known physiological characteristics, such as cytolytic and neurotoxic activities. However, there have been few studies on neurotoxic pept...
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Article
Cloaked caged glutamate eliminates off-target GABA-A receptor antagonism and opens a new door in neuroscience
Caged neurotransmitters are widely used to study neurobiological processes such as synaptic transmission and plasticity. However, uncaging has been primarily restricted to in vitro and ex vivo experimental system...
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Article
Association of glutathione S-transferase M1 and T1 null/present polymorphism with physical performance in the Korean population
Human physical performance is a highly complex phenotype that is influenced by various factors. In particular, genetic factors related to muscle fiber type, bone density, muscle performance, and metabolic proc...
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Article
Genetic associations between ADHD and dopaminergic genes (DAT1 and DRD4) VNTRs in Korean children
It is well known that dopaminergic genes affect the development of attention deficit hyperactivity disorder (ADHD) in various populations. Many studies have shown that variable number tandem repeats (VNTRs) lo...
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Article
Improvement in β-glucan extraction from Ganoderma lucidum with high-pressure steaming and enzymatic pre-treatment
In this study, the high-pressure steaming and enzymatic pre-treatment (SET) was used to improve β-glucan extraction from Ganoderma lucidum (G. lucidum), an oriental medicinal mushroom. Response surface methodolog...
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Article
Open AccessFabrication-Method-Dependent Excited State Dynamics in CH3NH3PbI3 Perovskite Films
Understanding the excited-state dynamics in perovskite photovoltaics is necessary for progress in these materials, but changes in dynamics depending on the fabrication processes used for perovskite photoactive...
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Article
Is there a relationship between PPARD T294C/PPARGC1A Gly482Ser variations and physical endurance performance in the Korean population?
The peroxisome proliferator-activated receptor δ (PPARD) and peroxisome proliferator-activated receptor γ coactivator 1α (PPARGC1A) genes recently have been suggested to have an association with athletic performa...
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Article
Association between glutathione S-transferases M1, T1 and P1 gene polymorphisms and prostate cancer in Koreans
Prostate cancer (PCa) is the most commonly diagnosed cancer in the developed world, and the incidence of this cancer is rising rapidly in many countries. Several polymorphic genes encoding enzymes involved car...
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Article
Phosphorylation of Ser-204 and Tyr-405 in human malonyl-CoA decarboxylase expressed in silkworm Bombyx mori regulates catalytic decarboxylase activity
Decarboxylation of malonyl-CoA to acetyl-CoA by malonyl-CoA decarboxylase (MCD; EC 4.1.1.9) is a vital catalytic reaction of lipid metabolism. While it is established that phosphorylation of MCD modulates the ...
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Article
Open AccessHuman acetyl-CoA carboxylase 2 expressed in silkworm Bombyx mori exhibits posttranslational biotinylation and phosphorylation
Biotin-dependent human acetyl-CoA carboxylases (ACCs) are integral in homeostatic lipid metabolism. By securing posttranslational biotinylation, ACCs perform coordinated catalytic functions allosterically regu...
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Article
Phenolics enrichment process from unripe apples
Unripe apples contain significant amount of phenolics with various health benefits. A pilot scale enrichment process of unripe apple phenolics with Viscozyme L extraction and XAD-7 sorption process, based on t...
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Article
Versatile surface plasmon resonance of carbon-dot-supported silver nanoparticles in polymer optoelectronic devices
The coupling of surface plasmons and excitons in organic materials can improve the performance of organic optoelectronic devices. Here, we prepare carbon-dot-supported silver nanoparticles (CD–Ag nanoparticles...
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Article
Optimization of enzymatic hydrolysis of persimmon peels for vinegar fermentation
Response surface methodology (RSM) was used to determine the treatment conditions of optimal enzymatic hydrolysis for vinegar preparation from persimmon peel. Persimmon peel was hydrolyzed with different conce...
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Article
The physicochemical properties and the antioxidant activities of persimmon peel powders with different particle sizes
To enhance utilization of persimmon peels as bio-resources, physicochemical properties and antioxidant activities of the powders obtained by drying, pulverization, and screening were investigated. Persimmon (D...
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Article
Optimization of carbohydrate-hydrolyzing enzyme aided polyphenol extraction from unripe apples
Unripe apples lie scattered about the orchards because of manual thinning out or falling, however they contain a high amount of polyphenol. In order to enhance the extraction of polyphenol from the unripe appl...
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Article
Enhancing polyphenol extraction from unripe apples by carbohydrate-hydrolyzing enzymes
The effects of process variables such as enzyme types, enzyme ratio, reaction temperature, pH, time, and ethanol concentration on the extraction of unripe apple polyphenol were investigated. The results indica...