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  1. Article

    Open Access

    Serotonin modulates excitatory synapse maturation in the develo** prefrontal cortex

    Serotonin (5-HT) imbalances in the develo** prefrontal cortex (PFC) are linked to long-term behavioral deficits. However, the synaptic mechanisms underlying 5-HT-mediated PFC development are unknown. We foun...

    Roberto Ogelman, Luis E. Gomez Wulschner, Victoria M. Hoelscher in Nature Communications (2024)

  2. No Access

    Article

    N-type Cav channel inhibition by spider venom peptide of Argiope bruennichi

    The spider venom is composed of various bioactive peptides and has well-known physiological characteristics, such as cytolytic and neurotoxic activities. However, there have been few studies on neurotoxic pept...

    In-Wook Hwang, Min Kyoung Shin, Yoo-Jung Lee in Molecular & Cellular Toxicology (2021)

  3. No Access

    Article

    Cloaked caged glutamate eliminates off-target GABA-A receptor antagonism and opens a new door in neuroscience

    Caged neurotransmitters are widely used to study neurobiological processes such as synaptic transmission and plasticity. However, uncaging has been primarily restricted to in vitro and ex vivo experimental system...

    Roberto Ogelman, In-Wook Hwang, Won Chan Oh in Lab Animal (2020)

  4. No Access

    Article

    Association of glutathione S-transferase M1 and T1 null/present polymorphism with physical performance in the Korean population

    Human physical performance is a highly complex phenotype that is influenced by various factors. In particular, genetic factors related to muscle fiber type, bone density, muscle performance, and metabolic proc...

    In Wook Hwang, Kicheol Kim, Bit Na Kwon, Hyung Jun Kim, Seung Hun Han in Genes & Genomics (2019)

  5. No Access

    Article

    Genetic associations between ADHD and dopaminergic genes (DAT1 and DRD4) VNTRs in Korean children

    It is well known that dopaminergic genes affect the development of attention deficit hyperactivity disorder (ADHD) in various populations. Many studies have shown that variable number tandem repeats (VNTRs) lo...

    Jun Ho Hong, In Wook Hwang, Myung Ho Lim, Ho Jang Kwon, Han Jun ** in Genes & Genomics (2018)

  6. No Access

    Article

    Improvement in β-glucan extraction from Ganoderma lucidum with high-pressure steaming and enzymatic pre-treatment

    In this study, the high-pressure steaming and enzymatic pre-treatment (SET) was used to improve β-glucan extraction from Ganoderma lucidum (G. lucidum), an oriental medicinal mushroom. Response surface methodolog...

    In-Wook Hwang, Bo-Min Kim, Young-Chan Kim, Sang-Han Lee in Applied Biological Chemistry (2018)

  7. Article

    Open Access

    Fabrication-Method-Dependent Excited State Dynamics in CH3NH3PbI3 Perovskite Films

    Understanding the excited-state dynamics in perovskite photovoltaics is necessary for progress in these materials, but changes in dynamics depending on the fabrication processes used for perovskite photoactive...

    In-Sik Kim, Cheol Jo, Rira Kang, Dong-Yu Kim, Seong-** Son in Scientific Reports (2017)

  8. No Access

    Article

    Is there a relationship between PPARD T294C/PPARGC1A Gly482Ser variations and physical endurance performance in the Korean population?

    The peroxisome proliferator-activated receptor δ (PPARD) and peroxisome proliferator-activated receptor γ coactivator 1α (PPARGC1A) genes recently have been suggested to have an association with athletic performa...

    Han-Jun **, In-Wook Hwang, Ki-Cheol Kim, Hyun-Ik Cho, Tae-Hwan Park in Genes & Genomics (2016)

  9. No Access

    Article

    Association between glutathione S-transferases M1, T1 and P1 gene polymorphisms and prostate cancer in Koreans

    Prostate cancer (PCa) is the most commonly diagnosed cancer in the developed world, and the incidence of this cancer is rising rapidly in many countries. Several polymorphic genes encoding enzymes involved car...

    Ye-Eun Shin, In-Wook Hwang, Han-Jun ** in Genes & Genomics (2016)

  10. No Access

    Article

    Phosphorylation of Ser-204 and Tyr-405 in human malonyl-CoA decarboxylase expressed in silkworm Bombyx mori regulates catalytic decarboxylase activity

    Decarboxylation of malonyl-CoA to acetyl-CoA by malonyl-CoA decarboxylase (MCD; EC 4.1.1.9) is a vital catalytic reaction of lipid metabolism. While it is established that phosphorylation of MCD modulates the ...

    In-Wook Hwang, Yu Makishima, Tomohiro Suzuki in Applied Microbiology and Biotechnology (2015)

  11. Article

    Open Access

    Human acetyl-CoA carboxylase 2 expressed in silkworm Bombyx mori exhibits posttranslational biotinylation and phosphorylation

    Biotin-dependent human acetyl-CoA carboxylases (ACCs) are integral in homeostatic lipid metabolism. By securing posttranslational biotinylation, ACCs perform coordinated catalytic functions allosterically regu...

    In-Wook Hwang, Yu Makishima, Tatsuya Kato in Applied Microbiology and Biotechnology (2014)

  12. No Access

    Article

    Phenolics enrichment process from unripe apples

    Unripe apples contain significant amount of phenolics with various health benefits. A pilot scale enrichment process of unripe apple phenolics with Viscozyme L extraction and XAD-7 sorption process, based on t...

    Hu-Zhe Zheng, In-Wook Hwang, Byoung-Kwan Kim in Journal of the Korean Society for Applied … (2014)

  13. No Access

    Article

    Versatile surface plasmon resonance of carbon-dot-supported silver nanoparticles in polymer optoelectronic devices

    The coupling of surface plasmons and excitons in organic materials can improve the performance of organic optoelectronic devices. Here, we prepare carbon-dot-supported silver nanoparticles (CD–Ag nanoparticles...

    Hyosung Choi, Seo-** Ko, Yuri Choi, Piljae Joo, Taehyo Kim, Bo Ram Lee in Nature Photonics (2013)

  14. No Access

    Article

    Optimization of enzymatic hydrolysis of persimmon peels for vinegar fermentation

    Response surface methodology (RSM) was used to determine the treatment conditions of optimal enzymatic hydrolysis for vinegar preparation from persimmon peel. Persimmon peel was hydrolyzed with different conce...

    In-Wook Hwang, Shin-Kyo Chung in Journal of the Korean Society for Applied … (2013)

  15. No Access

    Article

    The physicochemical properties and the antioxidant activities of persimmon peel powders with different particle sizes

    To enhance utilization of persimmon peels as bio-resources, physicochemical properties and antioxidant activities of the powders obtained by drying, pulverization, and screening were investigated. Persimmon (D...

    In-Wook Hwang, Moon-Cheol Jeong in Journal of the Korean Society for Applied … (2011)

  16. No Access

    Article

    Optimization of carbohydrate-hydrolyzing enzyme aided polyphenol extraction from unripe apples

    Unripe apples lie scattered about the orchards because of manual thinning out or falling, however they contain a high amount of polyphenol. In order to enhance the extraction of polyphenol from the unripe appl...

    Hu-Zhe Zheng, In-Wook Hwang, Suk-Kyung Kim in Journal of the Korean Society for Applied … (2010)

  17. No Access

    Article

    Enhancing polyphenol extraction from unripe apples by carbohydrate-hydrolyzing enzymes

    The effects of process variables such as enzyme types, enzyme ratio, reaction temperature, pH, time, and ethanol concentration on the extraction of unripe apple polyphenol were investigated. The results indica...

    Hu-zhe Zheng, In-Wook Hwang, Shin-Kyo Chung in Journal of Zhejiang University SCIENCE B (2009)