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Article
Open AccessEfficacy and safety of upadacitinib in patients with ankylosing spondylitis refractory to biologic therapy: 1-year results from the open-label extension of a phase III study
Upadacitinib, a Janus kinase inhibitor, has demonstrated efficacy and an acceptable safety profile in patients with ankylosing spondylitis (AS) in the phase III SELECT-AXIS programs. We report the 1-year effic...
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Article
Open AccessEffect of Upadacitinib on Disease Activity, Pain, Fatigue, Function, Health-Related Quality of Life and Work Productivity for Biologic Refractory Ankylosing Spondylitis
Patients with ankylosing spondylitis (AS) have significant unmet treatment needs, despite advancements in biologic therapies. This study evaluated the impact of upadacitinib on clinically meaningful improvemen...
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Article
Open AccessEfficacy and safety of upadacitinib in patients with active psoriatic arthritis and axial involvement: results from two phase 3 studies
The objective of this post-hoc analysis was to assess the efficacy and safety of upadacitinib in psoriatic arthritis (PsA) patients with axial involvement.
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Article
Open AccessRadiosynthesis and characterization of [18F]BS224: a next-generation TSPO PET ligand insensitive to the rs6971 polymorphism
Translocator protein 18-kDa (TSPO) positron emission tomography (PET) is a valuable tool to detect neuroinflammed areas in a broad spectrum of neurodegenerative diseases. However, the clinical application of s...
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Article
Open AccessBiodistribution and internal radiation dosimetry of a companion diagnostic radiopharmaceutical, [68Ga]PSMA-11, in subcutaneous prostate cancer xenograft model mice
[68Ga]PSMA-11 is a prostate-specific membrane antigen (PSMA)-targeting radiopharmaceutical for diagnostic PET imaging. Its application can be extended to targeted radionuclide therapy (TRT). In this study, we cha...
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Article
Temporal variation of sulfate concentration in PM2.5 and major factors enhancing sulfate concentration in the atmosphere of Seoul, Korea
Despite frequent observations of high particulate matter (PM) concentrations in Seoul, Korea, the sulfate (SO42−) concentrations in PM with an aerodynamic diameter below or equal to 2.5 μm (PM2.5) in Seoul have b...
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Article
The Long Term Trends of Tropospheric Ozone in Major Regions in Korea
This study was conducted for analyzing the contribution factors on ozone concentrations and its long term trends in each major city and province in Korea through several statistical methods such as simple line...
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Article
Open AccessCancer-targeted Nucleic Acid Delivery and Quantum Dot Imaging Using EGF Receptor Aptamer-conjugated Lipid Nanoparticles
Co-application of fluorescent quantum dot nanocrystals and therapeutics has recently become a promising theranostic methodology for cancer treatment. We developed a tumor-targeted lipid nanocarrier that demons...
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Article
Erratum to: Correlation of electrode position and clinical outcomes in Globus pallidus stimulation for dystonia
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Article
Correlation of electrode position and clinical outcomes in globus pallidus stimulation for dystonia
The correlation between the electrode location and the clinical outcome for internal globus pallidus (GPi) deep brain stimulation (DBS) has not been fully elucidated.
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Article
Open AccessGood correlation between changes in objective and subjective signs of inflammation in patients with short- but not long duration of axial spondyloarthritis treated with tumor necrosis factor-blockers
The aim of this study was to investigate the influence of symptom duration on treatment response and on the correlation between improvements in patient reported outcomes (PRO) and objective inflammation in pat...
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Article
Data format and browser of lightweight CAD files for dimensional verification over the internet
The demand for the use of 3D CAD data over the Internet environment has been increasing. However, CAD data size has deteriorated the communication effectiveness of 3D CAD files. Good design methodology of a li...
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Article
Development of an authoring framework for the simplified customization of PDM systems
Given that the amount of product data in firms is explosively increasing, a PDM system for effective data management is considered indispensable for product development. However, considerable time and speciali...
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Article
Internet-based dimensional verification system for reverse engineering processes
This paper proposes a design methodology for a Web-based collaborative system applicable to reverse engineering processes in a distributed environment. By using the developed system, design reviewers of new pr...
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Article
XML-based assembly visualization for a multi-CAD digital mock-up system
Using a virtual assembly tool, engineers are able to design accurate and interference free parts without making physical mock-ups. Instead of a single CAD source, several CAD systems are used to design a compl...
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Article
Interference verification of injection molds on the web-based CAD viewer
As the interference between mold parts occurs in a small region, it is difficult to find the interference at the design stage. It is usually found at the assembly stage of injection molds, which delays both de...
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Article
Diagnosing early ankylosing spondylitis
Diagnosis of ankylosing spondylitis is still delayed by many years. Several efforts have been made in the past few years to shorten this delay. A new set of criteria for inflammatory back pain has performed be...
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Article
Web-based CAD viewer with dimensional verification capability through the STEP translation server
To design a CAD viewer on the Web, a file translation system which converts a native CAD file of a commercial CAD to the simplified CAD file is required. However, commercial CAD viewers have used simplified ge...
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Chapter and Conference Paper
Multiscale Characteristics of Human Sleep EEG Time Series
We investigated the complexity of fluctuations in human sleep electroencephalograms (EEGs) by multifractals. We used human sleep EEG time series taken from normal, healthy subjects during the four stages of sl...
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Article
Simulation and experimental methods for media transport system: Part II, effect of normal force on slippage of paper
Many daily appliances for examples copiers, printers and ATMs contain the media transport system (MTS) and the slippage between the medium in the MTS deteriorates the performance quality of the whole system Th...
