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Open AccessIbrutinib induces chromatin reorganisation of chronic lymphocytic leukaemia cells
Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in Western countries. It has recently been shown that the homogeneity of the chromatin landscape between CLL cells contrasts with the important ...
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Article
Open AccessKinetic regulation of multi-ligand binding proteins
Second messengers, such as calcium, regulate the activity of multisite binding proteins in a concentration-dependent manner. For example, calcium binding has been shown to induce conformational transitions in ...
