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Article
Allele distribution and effect on reporter gene expression of vasopressin receptor gene (AVPR1a)-linked VNTR in primates
We surveyed repeat sequence in the 5′ flanking region of primate arginine vasopressin receptor 1a gene (AVPR1a) which is important for social behavior in mammals. The amplified region was polymorphic in length in...
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Article
Interspecies and intraspecies variations in the serotonin transporter gene intron 3 VNTR in nonhuman primates
A variable number of tandem repeat (VNTR) polymorphism based on a 16 or 17-bp unit has been reported in the third intron of the human serotonin transporter gene (5-HTT). VNTRs have been shown to affect the transc...
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Article
Development of the sexual skin with pubertal maturation in female chimpanzees
We examined the adolescent development of the sexual skin of chimpanzees (Pan troglodytes) by daily observation, evaluation of swelling, and weekly photogrametry. Although the size of swelling differed with the i...
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Article
Comparative analysis of estrogen receptor gene polymorphisms in apes
Polymorphic microsatellite repeats in the promoter region of estrogen receptor α gene (ESRα and the intron 6 region of estrogen receptor β gene (ESRβ) have been reported in human populations. To examine the evolu...
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Article
Comparison of androgen receptor CAG and GGN repeat length polymorphism in humans and apes
Two polymorphic trinucleotide repeats of human androgen receptor gene (hAR), CAG and GGN which encode glutamine and glycine, have been shown to be associated with human diseases. The number of repeats ranges from...
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Chapter
The Application of a Human Personality Test to Chimpanzees and Survey of Polymorphism in Genes Relating to Neurotransmitters and Hormones
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Article
Comparative Genetics of Functional Trinucleotide Tandem Repeats in Humans and Apes
Several human neurodegenerative disorders are caused by the expansion of polymorphic trinucleotide repeat regions. Many of these loci are functional short tandem repeats (STRs) located in brain-expressed genes...
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Article
Lineage-Specific Homogenization of the Polyubiquitin Gene Among Human and Great Apes
Ubiquitin is a highly conserved protein, and is encoded by a multigene family among eukaryote species. The polyubiquitin genes, UbB and UbC, comprise tandem multiple ubiquitin coding units without a spacer region...
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Article
Development of the hand and wrist bones in chimpanzees
Skeletal developmental of chimpanzees was studied cross-sectionally. By application of the TW2 method, we described the skeletal development of chimpanzees and compared their skeletal development with humans'....