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  1. Article

    Open Access

    Improving therapeutic protein secretion in the probiotic yeast Saccharomyces boulardii using a multifactorial engineering approach

    The probiotic yeast Saccharomyces boulardii (Sb) is a promising chassis to deliver therapeutic proteins to the gut due to Sb’s innate therapeutic properties, resistance to phage and antibiotics, and high protein ...

    Deniz Durmusoglu, Ibrahim Al’Abri, Zidan Li in Microbial Cell Factories (2023)

  2. Article

    Open Access

    Engineered cell differentiation and sexual reproduction in probiotic and mating yeasts

    G protein-coupled receptors (GPCRs) enable cells to sense environmental cues and are indispensable for coordinating vital processes including quorum sensing, proliferation, and sexual reproduction. GPCRs compr...

    Emil D. Jensen, Marcus Deichmann, **n Ma, Rikke U. Vilandt in Nature Communications (2022)