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Article

Efficacy of AAV serotypes to target Schwann cells after intrathecal and intravenous delivery

To optimize gene delivery to myelinating Schwann cells we compared clinically relevant AAV serotypes and injection routes. AAV9 and AAVrh10 vectors expressing either EGFP or the neuropathy-associated gene GJB1/Co...

A. Kagiava, J. Richter, C. Tryfonos, M. Leal-Julià, I. Sargiannidou… in Scientific Reports (2021)