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Article
Variability in Force Applied to the Head During Simulated Face Mask Ventilation on Manikins
Background and aims: Excessive force applied to the head during delivery may cause injury and bradycardia. Force applied during mask positive pressure ventilation (PPV) has not previously been reported.
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Article
Variability in Force Applied to the Head During Simulated Face Mask Ventilation on Manikins
Background and Aims: Excessive force applied to the head during delivery may cause injury and bradycardia. Force applied during mask positive pressure ventilation (PPV) has not previously been reported. Applied f...
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Chapter and Conference Paper
Are head injury guidelines changing the outcome of head injured children? A regional investigation
Background Secondary pathophysiological CPP insult is related to outcome after head injury, and improved management would be expected to reduce secondary brain insult. Paediatric head inj...
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Article
Modulating effect of apolipoprotein E polymorphisms on secondary brain insult and outcome after childhood brain trauma
The aim of this study was to determine the relationship between apolipoprotein E (APO E) alleles, the amount of cerebral perfusion pressure (CPP) insult and outcome in children after brain trauma.
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Chapter and Conference Paper
The measurement of brain tissue stiffness in-vivo
Background There is considerable interest in surgical decompression as a management strategy (RescueICP) for intractable intracranial hypertension. After such an operation measurements of intracr...
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Chapter and Conference Paper
Low frequency pressure waves of possible autonomic origin in severely head-injured children
Background Useful information (both clinical and patho-physiological) which may be extracted from intracranial pressure (ICP) recordings include: (1) the mean level of ICP (and CPP), (2) cerebrov...
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Article
The use of hyperventilation therapy after traumatic brain injury in Europe: an analysis of the BrainIT database
To assess the use of hyperventilation and the adherence to Brain Trauma Foundation-Guidelines (BTF-G) after traumatic brain injury (TBI).
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Chapter and Conference Paper
BrainIT: a trans-national head injury monitoring research network
Studies of therapeutic interventions and management strategies on head injured patients are difficult to undertake. BrainIT provides validated data for analysis available to centers that contribute data to all...
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Article
Age-related differences in intracranial pressure and cerebral perfusion pressure in the first 6 hours of monitoring after children’s head injury: association with outcome
Severe head injury in childhood is associated with considerable mortality and morbidity. In this study we determined age-related differences in the relationship between outcome and intracranial pressure (ICP) ...
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Chapter and Conference Paper
Clinical comparison of tympanic membrane displacement with invasive ICP measurements
Tympanic membrane displacement (TMD) measurements may be useful in the management of patients with hydrocephalus if they can be directly associated with measurements of ICP. We have compared TMD measurements u...
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Chapter and Conference Paper
Which paediatric head injured patients might benefit from decompression? Thresholds of ICP and CPP in the first six hours
Severe head injury in childhood continues to be associated with considerable mortality and morbidity. Early surgical decompression may be beneficial and the objective of this study was to examine the relations...
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Chapter and Conference Paper
Quantification of secondary CPP insult severity in paediatric head injured patients using a pressure-time index
This paper describes and validates a new Cumulative Pressure-Time Index (CPT) which takes into account both duration and degree of cerebral perfusion pressure (CPP) derangement and determines critical thresholds ...
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Chapter and Conference Paper
Bilateral ICP Monitoring: Its Importance in Detecting the Severity of Secondary Insults
The aim of head injury management is to prevent secondary insults to the damaged brain. Raised intracranial pressure and low cerebral perfusion pressure are two secondary insults which are important determinan...
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Chapter and Conference Paper
Clinical Evaluation of the Codman Microsensor Intracranial Pressure Monitoring System
Introduction: The use of the Camino fibre-optic subdural device for measuring Intracranial Pressure (ICP) in patients, has been shown to correlate well with recordings from the “gold standard” in...
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Chapter and Conference Paper
The Effect of Age on Cerebral Oedema, Cerebral Infarction and Neuroprotective Potential in Experimental Occlusive Stroke
A model of occlusive stroke in the aging brain has been developed and used to evaluate the effects of age upon cerebral infarction, cerebral oedema and neuroprotective potential. Focal ischaemia following left...
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Chapter and Conference Paper
Cerebral Oedema Following Intracerebral Haemorrhage: the Effect of the NMDA Receptor Antagonists MK-801 and D-CPPene
The effects of pre-treatment with the NMDA receptor antagonists MK-801 and D-CPPene on the development of brain oedema were investigated in a rodent model of intracerebral haemorrhage. In acute experiments (4 ...
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Article
Cerebral blood flow measurement using the hydrogen clearance technique: A microcomputer-based system for data collection and analysis
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Chapter and Conference Paper
Clinical Evaluation of the Camino Ventricular Bolt Pressure Monitoring System
Intracranial pressure (ICP) measurement is a routine part of the clinical management of severe head injury in many neurosurgical units. A variety of measurement techniques are available including ventricular a...
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Chapter and Conference Paper
Continuous Monitoring and Recording of Cerebral Perfusion Pressure
The measurement of intracranial pressure (ICP) and arterial blood pressure (BP) by invasive techniques in severely head injured patients is routine in many neurosurgical Intensive Care Units. The cerebral perf...
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Chapter and Conference Paper
Intracranial and Cerebral Perfusion Pressure Monitoring in the Head Injured Patient: Which Index?
For patients with severe head injury it is well known that intracranial pressure (ICP) and cerebral perfusion pressure (CPP) correlate with outcome. McGraw et al. [5] have shown that the length of time at a pr...
