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Adhesion-mediated cytoskeletal remodeling is controlled by the direct scaffolding of Src from FAK complexes to lipid rafts by SSeCKS/AKAP12
Metastatic cell migration and invasion are regulated by altered adhesion-mediated signaling to the actin-based cytoskeleton via activated Src–FAK complexes. Src-suppressed C-kinase substrate (SSeCKS, the roden...
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Article
PTPN14 interacts with and negatively regulates the oncogenic function of YAP
The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis. The pivotal effector of this pathway is YAP, a transcriptional c...
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Article
Reovirus infection of cancer cells is not due to activated Ras pathway