![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessAI-accelerated protein-ligand docking for SARS-CoV-2 is 100-fold faster with no significant change in detection
Protein-ligand docking is a computational method for identifying drug leads. The method is capable of narrowing a vast library of compounds down to a tractable size for downstream simulation or experimental te...
-
Article
Open AccessPublisher Correction: Converting tabular data into images for deep learning with convolutional neural networks
-
Article
Open AccessConverting tabular data into images for deep learning with convolutional neural networks
Convolutional neural networks (CNNs) have been successfully used in many applications where important information about data is embedded in the order of features, such as speech and imaging. However, most tabu...
-
Article
Open AccessLearning curves for drug response prediction in cancer cell lines
Motivated by the size and availability of cell line drug sensitivity data, researchers have been develo** machine learning (ML) models for predicting drug response to advance cancer treatment. As drug sensit...
-
Article
Open AccessEnsemble transfer learning for the prediction of anti-cancer drug response
Transfer learning, which transfers patterns learned on a source dataset to a related target dataset for constructing prediction models, has been shown effective in many applications. In this paper, we investig...
-
Article
Open AccessKBase: The United States Department of Energy Systems Biology Knowledgebase
-
Article
Open AccessDevelo** an in silico minimum inhibitory concentration panel test for Klebsiella pneumoniae
Antimicrobial resistant infections are a serious public health threat worldwide. Whole genome sequencing approaches to rapidly identify pathogens and predict antibiotic resistance phenotypes are becoming more ...
-
Protocol
Assembly, Annotation, and Comparative Genomics in PATRIC, the All Bacterial Bioinformatics Resource Center
In the “big data” era, research biologists are faced with analyzing new types that usually require some level of computational expertise. A number of programs and pipelines exist, but acquiring the expertise t...
-
Article
Erratum to: Evaluation of the efficacy of a pre-pandemic H5N1 vaccine (MG1109) in mouse and ferret models
-
Article
Evaluation of the efficacy of a pre-pandemic H5N1 vaccine (MG1109) in mouse and ferret models
The threat of a highly pathogenic avian influenza (HPAI) H5N1 virus causing the next pandemic remains a major concern. In this study, we evaluated the immunogenicity and efficacy of an inactivated whole-virus ...