29 Result(s)

Article

RETRACTED ARTICLE: Chronic NMDA administration to rats increases brain pro-apoptotic factors while decreasing anti-Apoptotic factors and causes cell death

Chronic N-Methyl-D-aspartate (NMDA) administration to rats is reported to increase arachidonic acid signaling and upregulate neuroinflammatory markers in rat brain. These changes may damage brain cells. In this s...

Hyung-Wook Kim, Yunyoung C Chang, Mei Chen, Stanley I Rapoport… in BMC Neuroscience (2009)

Article

Peroxisome proliferator-activated receptor-α activator fenofibrate prevents high-fat diet-induced renal lipotoxicity in spontaneously hypertensive rats

We investigated the effects of a high-fat (HF) diet and peroxisome proliferator-activated receptor (PPAR)-α activation on the intrarenal lipotoxicity associated with the renin–angiotensin system (RAS) and oxid...

Seok Joon Shin, Ji Hee Lim, Sung** Chung, Dong-Ye Youn… in Hypertension Research (2009)

Article

RETRACTED ARTICLE: Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in brain of HIV-1 transgenic rats

Cognitive impairment has been reported in human immune deficiency virus-1- (HIV-1-) infected patients as well as in HIV-1 transgenic (Tg) rats. This impairment has been linked to neuroinflammation, disturbed b...

Jagadeesh Sridhara Rao, Hyung-Wook Kim, Matthew Kellom… in Journal of Neuroinflammation (2011)

Article

Erratum to: Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in brain of HIV-1 transgenic rats

Correction to Rao J S, Kim H W, Kellom M, Greenstein D, Chen M, Kraft A D, Harry G J, Rapoport S I, Basselin M. Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, ...

Jagadeesh Sridhara Rao, Hyung-Wook Kim, Matthew Kellom… in Journal of Neuroinflammation (2012)

Article

Upregulated expression of brain enzymatic markers of arachidonic and docosahexaenoic acid metabolism in a rat model of the metabolic syndrome

In animal models, the metabolic syndrome elicits a cerebral response characterized by altered phospholipid and unesterified fatty acid concentrations and increases in pro-apoptotic inflammatory mediators that ...

Ameer Y Taha, Fei Gao, Epolia Ramadan, Yewon Cheon, Stanley I Rapoport… in BMC Neuroscience (2012)

Article

Plasma exchange successfully treats central pontine myelinolysis after acute hypernatremia from intravenous sodium bicarbonate therapy

Osmotic demyelination syndrome (ODS) primarily occurs after rapid correction of severe hyponatremia. There are no proven effective therapies for ODS, but we describe the first case showing the successful treat...

Kyung Yoon Chang, In-Hee Lee, Gi Jun Kim, Kangwon Cho, Hoon Suk Park… in BMC Nephrology (2014)

Article

Paclitaxel-incorporated nanoparticles using block copolymers composed of poly(ethylene glycol)/poly(3-hydroxyoctanoate)

Block copolymers composed of poly(3-hydroxyoctanoate) (PHO) and methoxy poly(ethylene glycol) (PEG) were synthesized to prepare paclitaxel-incorporated nanoparticle for antitumor drug delivery. In a ¹H-NMR study,...

Hyun Yul Kim, Je Ho Ryu, Chong Woo Chu, Gyung Mo Son… in Nanoscale Research Letters (2014)

Article

Resveratrol increases AdipoR1 and AdipoR2 expression in type 2 diabetic nephropathy

Adiponectin has multiple functions including insulin sensitization, anti-inflammation and antiatherogenesis in various organs. Adiponectin activates 5′-adenosine monophosphate-activated protein kinase (AMPK) a...

Hoon Suk Park, Ji Hee Lim, Min Young Kim, Yaeni Kim… in Journal of Translational Medicine (2016)

Article

Erratum to: Resveratrol increases AdipoR1 and AdipoR2 expression in type 2 diabetic nephropathy

Hoon Suk Park, Ji Hee Lim, Min Young Kim, Yaeni Kim… in Journal of Translational Medicine (2016)

Article

Conditional deletion of Ndufs4 in dopaminergic neurons promotes Parkinson’s disease-like non-motor symptoms without loss of dopamine neurons

Reduction of mitochondrial complex I activity is one of the major hypotheses for dopaminergic neuron death in Parkinson’s disease. However, reduction of complex I activity in all cells or selectively in dopami...

Won-Seok Choi, Hyung-Wook Kim, François Tronche, Richard D. Palmiter… in Scientific Reports (2017)

Article

Retraction Note to: Chronic NMDA administration to rats increases brain pro-apoptotic factors while decreasing anti-Apoptotic factors and causes cell death

Hyung-Wook Kim, Yunyoung C Chang, Mei Chen, Stanley I Rapoport… in BMC Neuroscience (2017)

Article

Retraction Note to: Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in brain of HIV-1 transgenic rats

Jagadeesh Sridhara Rao, Hyung-Wook Kim, Matthew Kellom… in Journal of Neuroinflammation (2017)

Article

Clinical outcomes of endoscopic submucosa dissection for high-grade dysplasia from endoscopic forceps biopsy

Although the Vienna Classification recommends endoscopic resection for gastric high-grade dysplasia (HGD), many resected lesions are diagnosed as gastric cancer after endoscopic resection. This study aims to e...

Dae Gon Ryu, Cheol Woong Choi, Dae Hwan Kang, Hyung Wook Kim, Su Bum Park… in Gastric Cancer (2017)

Article

Cinacalcet-mediated activation of the CaMKKβ-LKB1-AMPK pathway attenuates diabetic nephropathy in db/db mice by modulation of apoptosis and autophagy

Apoptosis and autophagy are harmoniously regulated biological processes for maintaining tissue homeostasis. AMP-activated protein kinase (AMPK) functions as a metabolic sensor to coordinate cellular survival a...

Ji Hee Lim, Hyung Wook Kim, Min Young Kim, Tae Woo Kim, Eun Nim Kim… in Cell Death & Disease (2018)

Article

Calcimimetic restores diabetic peripheral neuropathy by ameliorating apoptosis and improving autophagy

Decreased AMPK-eNOS bioavailability mediates the development of diabetic peripheral neuropathy (DPN) through increased apoptosis and decreased autophagy activity in relation to oxidative stress. Schwann cells ...

You Chul Chung, Ji Hee Lim, Hyun Mi Oh, Hyung Wook Kim… in Cell Death & Disease (2018)

Article

Risk factors for delayed bleeding by onset time after endoscopic submucosal dissection for gastric neoplasm

Post-endoscopic submucosal dissection bleeding (PEB) is one of the important complications after endoscopic submucosal dissection (ESD), but still difficult to predict. The present study aimed to identify sign...

Hyeong Seok Nam, Cheol Woong Choi, Su ** Kim, Hyung Wook Kim… in Scientific Reports (2019)

Article

Graft immaturity and safety concerns in transplanted human kidney organoids

For chronic kidney disease, regeneration of lost nephrons with human kidney organoids derived from induced pluripotent stem (iPS) cells is proposed to be an attractive potential therapeutic option. It remains ...

Sun Ah Nam, Eunjeong Seo, ** Won Kim, Hyung Wook Kim… in Experimental & Molecular Medicine (2019)

Article

Possible indication of endoscopic resection in undifferentiated early gastric cancer

Endoscopic resection for early gastric cancer (EGC) without lymph node metastasis may be a valuable treatment option. To date, endoscopic resection for undifferentiated EGC is being investigated. We evaluated ...

Dae Gon Ryu, Cheol Woong Choi, Su ** Kim, Dae Hwan Kang… in Scientific Reports (2019)

Article

Clinical outcomes of iatrogenic upper gastrointestinal endoscopic perforation: a 10-year study

Upper gastrointestinal endoscopic examination is a relatively safe procedure; however, all endoscopic procedures are invasive and are associated with a risk of iatrogenic perforation. To evaluate clinical outc...

Dae Hwan Kang, Dae Gon Ryu, Cheol Woong Choi, Hyung Wook Kim… in BMC Gastroenterology (2019)

Article

Correction to: Graft immaturity and safety concerns in transplanted human kidney organoids

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Sun Ah Nam, Eunjeong Seo, ** Won Kim, Hyung Wook Kim… in Experimental & Molecular Medicine (2020)