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    Yin-Yang 1 and Yin-Yang 2 exert opposing effects on the promoter activity of interleukin 4

    Interleukin (IL)-4 acts on T cells as a growth and activation factor, and promotes the differentiation of type 2 T helper cells. In T cells, expression of the gene encoding IL-4 is regulated by inducible or co...

    Sung Ho Lee, Young-Chang Cho, Hyung Min Jeong in Archives of Pharmacal Research (2016)

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    Bromopropane compounds inhibit osteogenesis by ERK-dependent Runx2 inhibition in C2C12 cells

    Bromopropane (BP) is a halogenated alkan compound used in various industries as chemical intermediates, extraction solvents, and degreasing compounds. Halogenated alkan compounds can damage the nervous system,...

    Hyung Min Jeong, You Hee Choi, Hye Gwang Jeong in Archives of Pharmacal Research (2014)

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    Inhibition of osteoblastic differentiation by warfarin and 18-α-glycyrrhetinic acid

    Anticoagulation therapy with vitamin K antagonists such as warfarin is widely used to prevent and treat stroke in patients with chronic atrial fibrillation or mechanical heart valves. Because vitamin K is an e...

    Hyung Min Jeong, Dong Hyeok Cho, Yun Hye ** in Archives of Pharmacal Research (2011)

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    PKA-Mediated stabilization of FoxH1 negatively regulates ERα activity

    Estrogen receptor α (ERα) mediates the mitogenic effects of estrogen. ERα signaling regulates the normal growth and differentiation of mammary tissue, but uncontrolled ERα activation increases the risk to brea...

    **ah Yum, Hyung Min Jeong, Seulki Kim, ** Won Seo, Younho Han in Molecules and Cells (2009)