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Article
Ultrasensitive Detection of Ovarian Cancer Biomarker Using Au Nanoplate SERS Immunoassay
Ovarian cancer is the fifth leading cause of cancer-related deaths among women. In particular, it is a high cause of mortality among women in industrialized countries. Human epididymis protein 4 (HE4) has rece...
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Article
Open AccessUltrasensitive nucleic acid detection based on phosphorothioated hairpin-assisted isothermal amplification
Herein, we describe a phosphorothioated hairpin-assisted isothermal amplification (PHAmp) method for detection of a target nucleic acid. The hairpin probe (HP) is designed to contain a 5′ phosphorothioate (PS)...
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Article
Open AccessColorimetric detection of individual biothiols by tailor made reactions with silver nanoprisms
We herein described a rapid, sensitive, and selective colorimetric sensing platform for biothiols in human serum, which relies on the dual functions of biothiols as anti-etching and aggregating agent for silve...
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Article
Washing-free Electrochemical Strategy to Detect Target DNA Utilizing Peroxidase Mimicking DNAzyme
We herein describe a novel washing-free electrochemical strategy for target DNA detection by utilizing the peroxidase mimicking DNAzyme. The DNAzymeincorporated DNA probes, the key components of this strategy,...
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Article
Derivation of equations of motion of an unwinding cable considering transient-state tensile force in time-varying unwinding velocity
Unwinding dynamics refers to the study of nonlinear behaviour, tension profile, entangling, and fracturing in the process of unwinding a fibre from a package through the guide eyelet at a specific unwinding sp...
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Article
Open AccessInteractions between subjective memory complaint and objective cognitive deficit on memory performances
Subjective memory complaint (SMCs) is a common trait amongst older population. The subjective cognition about their memory could depend on objective cognition. The aim of the current study was to examine the i...
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Article
Open AccessLabel-free and washing-free alkaline phosphatase assay using a personal glucose meter
We herein describe a personal glucose meter (PGM)-based method for a label-free and washing-free determination of alkaline phosphatase (ALP) activity, which relies on the cascade enzymatic reactions promoted b...
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Article
Sensitive detection of DNA from Chlamydia trachomatis by using flap endonuclease-assisted amplification and graphene oxide-based fluorescence signaling
A simple and sensitive method is described for the determination of DNA. It relies on the use of (a) an invasive reaction that is catalyzed by flap endonuclease 1 (FEN 1), and (b) graphene oxide (GO)-based flu...
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Article
Determination of RNase H activity via real-time monitoring of target-triggered rolling circle amplification
The authors describe a method for real-time monitoring of the activity of ribonuclease H (RNase H). It is based on target-triggered rolling circle amplification (RCA). It utilizes a specially designed primer t...
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Article
Open AccessIn-vitro cytotoxicity assessment of carbon-nanodot-conjugated Fe-aminoclay (CD-FeAC) and its bio-imaging applications
We have investigated the cytotoxic assay of Fe-aminoclay (FeAC) nanoparticles (NPs) and simultaneous imaging in HeLa cells by photoluminescent carbon nanodots (CD) conjugation. Non-cytotoxic, photostable, and ...
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Article
Large genomic rearrangement of BRCA1 and BRCA2 genes in familial breast cancer patients in Korea
We screened large genomic rearrangements of the BRCA1 and BRCA2 genes in Korean, familial breast cancer patients. Multiplex ligation-dependent probe amplification assay was used to identify BRCA1 and BRCA2 genomi...
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Article
Open AccessPhotoluminescent carbon nanotags from harmful cyanobacteria for drug delivery and imaging in cancer cells
Using a simple method of mass production of green carbon nanotags (G-tags) from harmful cyanobacteria, we developed an advanced and efficient imaging platform for the purpose of anticancer therapy. Approximate...
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Article
High-throughput nanoscale lipid vesicle synthesis in a semicircular contraction-expansion array microchannel
Towards potential applications in the field of nanomedicine, a new high-throughput synthesis method of lipid vesicles with tunable size as well as enhanced monodispersity is demonstrated using a semicircular c...
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Chapter and Conference Paper
Gold Nanoparticles - based Colorimetric Single Nucleotide Polymorphisms Genoty** Utilizing Allele-specific PCR
A very convenient colorimetric method for the identification of single nucleotide polymorphism was developed utilizing gold nanoparticles and an allele-specific polymerase chain reaction and its diagnostic cap...
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Chapter and Conference Paper
Metal Ions-Triggered Polymerase Activity and Its Use for the Development of Molecular Logic Gates
We described a new strategy in which a polymerase enzyme is controlled to accomplish an unnatural extension reaction even at the mismatched site of a primer with template DNA. The validity of this novel concep...
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Article
An anisotropic snowflake-like structural assembly of polymer-capped gold nanoparticles
Snowflake-like structural assembly of isotropic gold nanoparticles (GNPs) is reported. A modified polyamine method has been employed to synthesize positively charged GNPs in presence of a polymeric metaphospha...
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Article
Economic evaluation of off-gas recycle pressure swing adsorption (PSA) in industrial scale poly(3-hydroxybutyrate) fermentation
The use of high purity oxygen as a feeding gas in microbial fermentation has recent gained huge attention in industrial scale process due to its advantageous effect to increase viable cell density as well as t...
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Article
A color display system based on thermochromic conjugated polydiacetylene supramolecules
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Article
Microarray-based detection of Korean-specific BRCA1 mutations
A reliable multiplex assay procedure to detect human genetic mutations in the breast cancer susceptibility gene BRCA1 using zip-code microarrays and single base extension (SBE) reactions is described. Multiplex P...
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Article
Radiolytic synthesis of Ag-loaded polystyrene (Ag-PS) nanoparticles and their antimicrobial efficiency againststaphylococcus aureus andklebsiella pneumoniase
Ag nanoparticles were distributed onto polystyrene nanoparticle (PS-Ag) beads using two synthetic methodologies. In the first methodology, polystyrene (PS) beads were prepared via emulsion polymerization, with...