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  1. No Access

    Article

    Ultrasensitive Detection of Ovarian Cancer Biomarker Using Au Nanoplate SERS Immunoassay

    Ovarian cancer is the fifth leading cause of cancer-related deaths among women. In particular, it is a high cause of mortality among women in industrialized countries. Human epididymis protein 4 (HE4) has rece...

    Gayoung Eom, Ahreum Hwang, Hongki Kim, Jeong Moon, Hyunju Kang in BioChip Journal (2021)

  2. Article

    Open Access

    Ultrasensitive nucleic acid detection based on phosphorothioated hairpin-assisted isothermal amplification

    Herein, we describe a phosphorothioated hairpin-assisted isothermal amplification (PHAmp) method for detection of a target nucleic acid. The hairpin probe (HP) is designed to contain a 5′ phosphorothioate (PS)...

    Yu** Jung, Jayeon Song, Hyun Gyu Park in Scientific Reports (2021)

  3. Article

    Open Access

    Colorimetric detection of individual biothiols by tailor made reactions with silver nanoprisms

    We herein described a rapid, sensitive, and selective colorimetric sensing platform for biothiols in human serum, which relies on the dual functions of biothiols as anti-etching and aggregating agent for silve...

    Pei Li, Sang Mo Lee, Hyo Yong Kim, Soohyun Kim, Steve Park in Scientific Reports (2021)

  4. No Access

    Article

    Washing-free Electrochemical Strategy to Detect Target DNA Utilizing Peroxidase Mimicking DNAzyme

    We herein describe a novel washing-free electrochemical strategy for target DNA detection by utilizing the peroxidase mimicking DNAzyme. The DNAzymeincorporated DNA probes, the key components of this strategy,...

    Sang Mo Lee, Sujeong Shin, Hyo Yong Kim in Biotechnology and Bioprocess Engineering (2020)

  5. No Access

    Article

    Derivation of equations of motion of an unwinding cable considering transient-state tensile force in time-varying unwinding velocity

    Unwinding dynamics refers to the study of nonlinear behaviour, tension profile, entangling, and fracturing in the process of unwinding a fibre from a package through the guide eyelet at a specific unwinding sp...

    **-Seok Jang, Kun-Woo Kim, Ji-Heon Kang, Hyun-Gyu Park in Nonlinear Dynamics (2020)

  6. Article

    Open Access

    Interactions between subjective memory complaint and objective cognitive deficit on memory performances

    Subjective memory complaint (SMCs) is a common trait amongst older population. The subjective cognition about their memory could depend on objective cognition. The aim of the current study was to examine the i...

    Soowon Park, Ji-Hye Lee, Jiyeon Lee, Youngsung Cho, Hyun Gyu Park in BMC Geriatrics (2019)

  7. Article

    Open Access

    Label-free and washing-free alkaline phosphatase assay using a personal glucose meter

    We herein describe a personal glucose meter (PGM)-based method for a label-free and washing-free determination of alkaline phosphatase (ALP) activity, which relies on the cascade enzymatic reactions promoted b...

    Jun Ki Ahn, Hyo Yong Kim, Chang Yeol Lee, Ki Soo Park in Journal of Biological Engineering (2019)

  8. No Access

    Article

    Sensitive detection of DNA from Chlamydia trachomatis by using flap endonuclease-assisted amplification and graphene oxide-based fluorescence signaling

    A simple and sensitive method is described for the determination of DNA. It relies on the use of (a) an invasive reaction that is catalyzed by flap endonuclease 1 (FEN 1), and (b) graphene oxide (GO)-based flu...

    Chang Yeol Lee, Hyowon Jang, Hansol Kim, Yu** Jung, Ki Soo Park in Microchimica Acta (2019)

  9. No Access

    Article

    Determination of RNase H activity via real-time monitoring of target-triggered rolling circle amplification

    The authors describe a method for real-time monitoring of the activity of ribonuclease H (RNase H). It is based on target-triggered rolling circle amplification (RCA). It utilizes a specially designed primer t...

    Chang Yeol Lee, Kyoung Suk Kang, Ki Soo Park, Hyun Gyu Park in Microchimica Acta (2017)

  10. Article

    Open Access

    In-vitro cytotoxicity assessment of carbon-nanodot-conjugated Fe-aminoclay (CD-FeAC) and its bio-imaging applications

    We have investigated the cytotoxic assay of Fe-aminoclay (FeAC) nanoparticles (NPs) and simultaneous imaging in HeLa cells by photoluminescent carbon nanodots (CD) conjugation. Non-cytotoxic, photostable, and ...

    Kyoung Suk Kang, Hyun Uk Lee, Moon Il Kim, So Young Park in Journal of Nanobiotechnology (2015)

  11. No Access

    Article

    Large genomic rearrangement of BRCA1 and BRCA2 genes in familial breast cancer patients in Korea

    We screened large genomic rearrangements of the BRCA1 and BRCA2 genes in Korean, familial breast cancer patients. Multiplex ligation-dependent probe amplification assay was used to identify BRCA1 and BRCA2 genomi...

    Ja Young Cho, Dae-Yeon Cho, Sei Hyun Ahn, Su-Youn Choi, Inkyung Shin in Familial Cancer (2014)

  12. Article

    Open Access

    Photoluminescent carbon nanotags from harmful cyanobacteria for drug delivery and imaging in cancer cells

    Using a simple method of mass production of green carbon nanotags (G-tags) from harmful cyanobacteria, we developed an advanced and efficient imaging platform for the purpose of anticancer therapy. Approximate...

    Hyun Uk Lee, So Young Park, Eun Sik Park, Byoungchul Son in Scientific Reports (2014)

  13. No Access

    Article

    High-throughput nanoscale lipid vesicle synthesis in a semicircular contraction-expansion array microchannel

    Towards potential applications in the field of nanomedicine, a new high-throughput synthesis method of lipid vesicles with tunable size as well as enhanced monodispersity is demonstrated using a semicircular c...

    Jisun Lee, Myung Gwon Lee, Cheulhee Jung, Youn-Hee Park, Chaeyeon Song in BioChip Journal (2013)

  14. No Access

    Chapter and Conference Paper

    Gold Nanoparticles - based Colorimetric Single Nucleotide Polymorphisms Genoty** Utilizing Allele-specific PCR

    A very convenient colorimetric method for the identification of single nucleotide polymorphism was developed utilizing gold nanoparticles and an allele-specific polymerase chain reaction and its diagnostic cap...

    Ye Lim Jung, Cheulhee Jung, Harshala Parab in 5th European Conference of the Internation… (2012)

  15. No Access

    Chapter and Conference Paper

    Metal Ions-Triggered Polymerase Activity and Its Use for the Development of Molecular Logic Gates

    We described a new strategy in which a polymerase enzyme is controlled to accomplish an unnatural extension reaction even at the mismatched site of a primer with template DNA. The validity of this novel concep...

    Ki Soo Park, Cheulhee Jung, Hyun Gyu Park in 5th European Conference of the Internation… (2012)

  16. No Access

    Article

    An anisotropic snowflake-like structural assembly of polymer-capped gold nanoparticles

    Snowflake-like structural assembly of isotropic gold nanoparticles (GNPs) is reported. A modified polyamine method has been employed to synthesize positively charged GNPs in presence of a polymeric metaphospha...

    Harshala Parab, Cheulhee Jung, Min-Ah Woo in Journal of Nanoparticle Research (2011)

  17. No Access

    Article

    Economic evaluation of off-gas recycle pressure swing adsorption (PSA) in industrial scale poly(3-hydroxybutyrate) fermentation

    The use of high purity oxygen as a feeding gas in microbial fermentation has recent gained huge attention in industrial scale process due to its advantageous effect to increase viable cell density as well as t...

    Ho Nam Chang, Moon Il Kim, Qiang Fei in Biotechnology and Bioprocess Engineering (2010)

  18. No Access

    Article

    A color display system based on thermochromic conjugated polydiacetylene supramolecules

    Oktay Yarimaga, Maesoon Im, Yang-Kyu Choi, Tae Won Kim in Macromolecular Research (2010)

  19. No Access

    Article

    Microarray-based detection of Korean-specific BRCA1 mutations

    A reliable multiplex assay procedure to detect human genetic mutations in the breast cancer susceptibility gene BRCA1 using zip-code microarrays and single base extension (SBE) reactions is described. Multiplex P...

    Cheulhee Jung, Seong-Chun Yim, Dae-Yeon Cho in Analytical and Bioanalytical Chemistry (2008)

  20. No Access

    Article

    Radiolytic synthesis of Ag-loaded polystyrene (Ag-PS) nanoparticles and their antimicrobial efficiency againststaphylococcus aureus andklebsiella pneumoniase

    Ag nanoparticles were distributed onto polystyrene nanoparticle (PS-Ag) beads using two synthetic methodologies. In the first methodology, polystyrene (PS) beads were prepared via emulsion polymerization, with...

    Geong-Dae Oh, Bok-Soo Byun, Seungho Lee, Seong-Ho Choi in Macromolecular Research (2007)

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