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  1. No Access

    Article

    Keratinized tissue augmentation using collagen-based soft tissue substitute with/without epidermal growth factor on buccally positioned implants: a pilot preclinical study

    To investigate the effect of epithelial growth factor (EGF) with collagen matrix (CM) on the gain of KT for buccally positioned implants in dogs.

    Hyun-Chang Lim, Chang-Hoon Kim, Heejun Yoon, Sunmin Lee in Clinical Oral Investigations (2023)

  2. No Access

    Article

    Effectiveness of hydraulic pressure-assisted sinus augmentation in a rabbit sinus model: a preclinical study

    To investigate the effectiveness of hydraulic pressure-assisted sinus augmentation (SA) in a rabbit sinus model in terms of radiographical and histological healing.

    Ji-Yeong Lee, Sangyup Kim, Seung-Yun Shin, Jong-Hyuk Chung in Clinical Oral Investigations (2022)

  3. Article

    Open Access

    A case series of profilometric changes in two implant placement protocols at periodontally compromised non-molar sites

    Information regarding profilometric changes at a soft tissue level following implant placement with different protocols is insufficient. Therefore, this study aimed to comparatively investigate the profilometr...

    Kwantae Noh, Daniel S. Thoma, Jung-Chul Park, Dong-Woon Lee in Scientific Reports (2021)

  4. No Access

    Article

    Overaugmentation to compensate for postextraction ridge atrophy using a putty-type porcine bone substitute material with recombinant bone morphogenetic protein-2: 4 weeks of healing in a canine model

    The aims of the present study were (i) to determine the short-term effects of putty-type porcine bone substitute material (PB) with recombinant bone morphogenetic protein-2 (rhBMP-2) for alveolar ridge preserv...

    Hyun-Chang Lim, So-Ra Yoon, Jae-Kook Cha, Jung-Seok Lee in Clinical Oral Investigations (2019)

  5. No Access

    Article

    A retrospective comparison of three modalities for vestibuloplasty in the posterior mandible: apically positioned flap only vs. free gingival graft vs. collagen matrix

    This work aimed to comparatively evaluate the three modalities of vestibuloplasty around implants in the posterior mandible.

    Hyun-Chang Lim, Sang-Chun An, Dong-Woon Lee in Clinical Oral Investigations (2018)

  6. No Access

    Article

    Sinus floor elevation using implants coated with recombinant human bone morphogenetic protein-2: micro-computed tomographic and histomorphometric analyses

    The objective of this study was to determine the validity of a graft-free sinus floor elevation (SFE) procedure with simultaneous placement of recombinant morphogenetic protein-2 (rhBMP-2)-coated implants comp...

    Daniel S. Thoma, So-Ra Yoon, Jae-Kook Cha, Hyun-Chang Lim in Clinical Oral Investigations (2018)

  7. No Access

    Article

    Sonic Hedgehog Promotes Cementoblastic Differentiation via Activating the BMP Pathways

    Although sonic hedgehog (SHH), an essential molecule in embryogenesis and organogenesis, stimulates proliferation of human periodontal ligament (PDL) stem cells, the effects of recombinant human SHH (rh-SHH) o...

    Won-Jung Bae, Q-Schick Auh, Hyun-Chang Lim, Gyu-Tae Kim in Calcified Tissue International (2016)

  8. Article

    Open Access

    Guided bone regeneration using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC)-cross-linked type-I collagen membrane with biphasic calcium phosphate at rabbit calvarial defects

    In-vitro and animal studies using EDC cross-linked membranes have shown great resistance to enzymatic digestion as well as low cytotoxicity, and indicated its potential expediency as a barrier ...

    **-Young Park, Im-Hee Jung, You-Kyoung Kim, Hyun-Chang Lim in Biomaterials Research (2015)

  9. Article

    Open Access

    Regeneration of rabbit calvarial defects using cells-implanted nano-hydroxyapatite coated silk scaffolds

    The aim of this study was to characterize the efficacy of nano-hydroxyapatite-coated silk fibroin constructs as a scaffold for bone tissue engineering and to determine the osteogenic effect of human dental pul...

    **-Young Park, Cheryl Yang, Im-Hee Jung, Hyun-Chang Lim in Biomaterials Research (2015)

  10. Article

    Open Access

    Comparative evaluation of biphasic calcium phosphate and biphasic calcium phosphate collagen composite on osteoconductive potency in rabbit calvarial defect

    The aim of this study was to determine the osteoconductivity of biphasic calcium phosphate collagen composite (BCPC) in rabbit calvarial defect model by comparing with biphasic calcium phosphate (BCP). Four 8 ...

    Eun-Ung Lee, Dong-Ju Kim, Hyun-Chang Lim, Jung-Seok Lee in Biomaterials Research (2015)

  11. Article

    Open Access

    Biocompatibility and resorption pattern of newly developed hyaluronic acid hydrogel reinforced three-layer poly (lactide-co-glycolide) membrane: histologic observation in rabbit calvarial defect model

    The aim of this study was to evaluate the biocompatibility and resorption pattern in three-layer poly (lactide-co-glycolide) (PLGA) membrane according to the concentrations of hyaluronic acid (HA) hydrogel in ...

    Hoon You, Eun-Ung Lee, You-Kyoung Kim, Bum-Chul Kim in Biomaterials Research (2014)